抗过敏药物对P物质诱导大鼠腹膜肥大细胞释放组胺的影响。
Effect of antianaphylactic agents on substance-P induced histamine release from rat peritoneal mast cells.
作者信息
Hachisuka H, Nomura H, Sakamoto F, Mori O, Okubo K, Sasai Y
机构信息
Department of Dermatology, Kurume University School of Medicine, Japan.
出版信息
Arch Dermatol Res. 1988;280(3):158-62. doi: 10.1007/BF00456847.
PMID:2454082
Abstract
Substance P is known to be a potent histamine liberator for mast cells. The influence of antianaphylactic agents, disodium cromoglycate (DSCG), ketotifen, and tranilast was studied on substance-P and compound 48/80-induced histamine release from rat peritoneal mast cells. Substance-P induced histamine release was inhibited by these agents, while compound 48/80-induced histamine release was not inhibited by tranilast. Our findings suggest that these antianaphylactic agents are assumed to be effective for cutaneous diseases which might be concerned with substance P and histamine.
摘要
已知P物质是肥大细胞的一种强效组胺释放剂。研究了抗组胺药色甘酸二钠（DSCG）、酮替芬和曲尼司特对P物质和化合物48/80诱导的大鼠腹膜肥大细胞组胺释放的影响。这些药物可抑制P物质诱导的组胺释放，而曲尼司特对化合物48/80诱导的组胺释放无抑制作用。我们的研究结果表明，这些抗组胺药可能对可能与P物质和组胺有关的皮肤病有效。
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本文引用的文献
1
An unidentified depressor substance in certain tissue extracts.某些组织提取物中一种不明的降压物质。
J Physiol. 1931 Jun 6;72(1):74-87. doi: 10.1113/jphysiol.1931.sp002763.
2
[Central transmission of afferent impulses. III. Incidence and significance of the substance P in the dorsal roots of the spinal cord].[传入冲动的中枢传导。III. 脊髓背根中P物质的发生率及意义]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;219(3):197-213.
3
Effect of N-5' on histamine release from rat peritoneal exudate cells induced by calcium ionophore and ATP.N-5' 对钙离子载体和ATP诱导的大鼠腹腔渗出细胞组胺释放的影响。
Jpn J Pharmacol. 1984 Jan;34(1):9-14. doi: 10.1254/jjp.34.9.
4
Localization of substance P-immunoreactive nerve fibers in the human digital skin.P物质免疫反应性神经纤维在人手指皮肤中的定位。
Experientia. 1983 Sep 15;39(9):1018-20. doi: 10.1007/BF01989781.
5
The role of the N-terminal tetrapeptide in the histamine releasing action of substance P.N端四肽在P物质组胺释放作用中的角色。
Neuropharmacology. 1981 Nov;20(11):1025-7. doi: 10.1016/0028-3908(81)90091-5.
6
Studies on pruritogenic and histamine-releasing effects of some putative peptide neurotransmitters.
Acta Derm Venereol. 1981;61(3):245-50.
7
Postocclusive cutaneous vasodilatation mediated by substance P.由P物质介导的闭塞后皮肤血管扩张
Naunyn Schmiedebergs Arch Pharmacol. 1981 Apr;316(2):165-71. doi: 10.1007/BF00505312.
8
Somatostatin-induced histamine secretion in mast cells. Characterization of the effect.生长抑素诱导肥大细胞分泌组胺。效应特征
Eur J Pharmacol. 1981 Jan 16;69(2):127-37. doi: 10.1016/0014-2999(81)90407-6.
9
Synthesis of granuliberin-R and various fragment peptides and their histamine-releasing activities.
Chem Pharm Bull (Tokyo). 1980 Mar;28(3):887-92. doi: 10.1248/cpb.28.887.
10
Amino-acid sequence of substance P.P物质的氨基酸序列。
Nat New Biol. 1971 Jul 21;232(29):86-7. doi: 10.1038/newbio232086a0.
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