Suppr超能文献

新西兰受伤患者与普通人群对EQ-5D健康状态的估值比较。

A comparison of injured patient and general population valuations of EQ-5D health states for New Zealand.

作者信息

Wilson Ross, Hansen Paul, Langley John, Derrett Sarah

机构信息

Department of Economics, University of Otago, Dunedin 9054, New Zealand.

出版信息

Health Qual Life Outcomes. 2014 Feb 18;12:21. doi: 10.1186/1477-7525-12-21.

Abstract

BACKGROUND

A near-universal finding internationally is that patient valuations of their own health, represented using the EQ-5D system, are mostly higher than general population valuations of the same EQ-5D states. This paper investigates whether this result also applies to New Zealand. Despite the EQ-5D's widespread use for cost-utility analysis in New Zealand, in particular by the Pharmaceutical Management Agency (PHARMAC) for health technology assessments, no previous studies comparing patient and general population valuations have included data for New Zealand.

METHODS

Valuations of 13 EQ-5D health states from a 1999 survey of the New Zealand general population (n = 396) are compared with injured New Zealanders' (n = 2099) valuations of their own health (also represented on the EQ-5D) collected between 2007 and 2009 in the Prospective Outcomes of Injury Study. Which EQ-5D dimensions are most strongly associated with the population valuations is also investigated.

RESULTS

Injured population valuations are higher (better-rated health) than general population valuations for all 13 health states considered except 11111 (no problems on any EQ-5D dimension). This difference, which tends to be larger the 'worse' the state, is statistically significant at the 10% level for most of the states. State 11111 is rated significantly lower by the injured population than the general population. Pain/discomfort is more important in determining valuations for the general population than for injured people, whereas problems with self-care are more important for the injured population; anxiety/depression is important in both general and injured population valuations.

CONCLUSIONS

Consistent with the international literature, injured people's valuations of their own health are mostly higher than the general population's hypothetical valuations of the same EQ-5D states for New Zealand. These differences are practically significant in the sense that they are larger than minimally important differences for the EQ-5D from the literature, and they appear capable of significantly affecting CUA results.

摘要

背景

国际上一个几乎普遍的发现是,使用EQ-5D系统表示的患者对自身健康的估值大多高于一般人群对相同EQ-5D状态的估值。本文研究这一结果是否也适用于新西兰。尽管EQ-5D在新西兰广泛用于成本效用分析,尤其是药物管理局(PHARMAC)用于卫生技术评估,但此前没有比较患者和一般人群估值的研究纳入新西兰的数据。

方法

将1999年对新西兰一般人群(n = 396)的13种EQ-5D健康状态估值,与2007年至2009年在“损伤前瞻性结果研究”中收集的受伤新西兰人(n = 2099)对自身健康的估值(也用EQ-5D表示)进行比较。还研究了哪些EQ-5D维度与人群估值关联最为紧密。

结果

除了11111(在任何EQ-5D维度上均无问题)之外,在所考虑的所有13种健康状态下,受伤人群的估值都高于一般人群的估值(健康评级更好)。这种差异往往在状态“越差”时越大,对于大多数状态在10%的水平上具有统计学显著性。受伤人群对11111状态的评级显著低于一般人群。对于一般人群而言,疼痛/不适在确定估值方面比受伤人群更重要,而自理问题对受伤人群更重要;焦虑/抑郁在一般人群和受伤人群的估值中都很重要。

结论

与国际文献一致,对于新西兰而言,受伤人群对自身健康的估值大多高于一般人群对相同EQ-5D状态的假设估值。这些差异在实际意义上是显著的,因为它们大于文献中EQ-5D的最小重要差异量级,并且似乎能够显著影响成本效用分析结果。

相似文献

9
Performance of the EQ-5D in patients with irritable bowel syndrome.EQ-5D在肠易激综合征患者中的表现。
Value Health. 2006 Mar-Apr;9(2):90-7. doi: 10.1111/j.1524-4733.2006.00086.x.

引用本文的文献

本文引用的文献

6
Prospective outcomes of injury study.前瞻性损伤研究结果。
Inj Prev. 2009 Oct;15(5):e3. doi: 10.1136/ip.2009.022558a.
10
The transient nature of utilities and health preferences.
Med Decis Making. 2006 Jul-Aug;26(4):304-6. doi: 10.1177/0272989X06290977.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验