Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China.
J Antibiot (Tokyo). 2014 May;67(5):401-3. doi: 10.1038/ja.2014.6. Epub 2014 Feb 19.
Two new α-pyrone derivatives, infectopyrones A (1) and B (2), were obtained from the EtOAc extract of the endophytic fungus Stemphylium sp. 33231 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds 1 and 2 were evaluated for their antibacterial activities, and they had a broad spectrum of antibacterial activity against five terrestrial pathogenic bacteria.
从南海采集的红树植物角果木（Bruguiera sexangula var. rhynchopetala）内生真菌 Stemphylium sp. 33231 的 EtOAc 提取物中分离得到两个新的α-吡喃酮衍生物，命名为 infectopyrones A（1）和 B（2）。通过综合光谱数据分析详细解析了它们的结构。对化合物 1 和 2 进行了抗菌活性评价，它们对 5 种陆地病原菌具有广谱的抗菌活性。
