Chávez Katiuska, Compagnoneb Reinaldo S, Riina Ricarda, Briceño Alexander, González Teresa, Squitieri Emilio, Landaetab Carlos, Soscrún Humberto, Suáreza Alírica I
Universidad Central de Venezuela, Caracas, Venezuela.
Escuela de Quimica, Facultad de Ciencias, Universidad Central de Venezuela, Caracas, Venezuela.
Nat Prod Commun. 2013 Dec;8(12):1679-82.
Four new crotofolane-type diterpenoids, crotocarasin (A-D) (1-4), together with the known crotofolin E, were isolated from a dichloromethane extract of the stems of Croton caracasanus Pittier. The structures of the new compounds were determined by spectroscopic methods, and the structure of 3 was further confirmed by single-crystal X-ray data analyses.
从加勒比巴豆(Croton caracasanus Pittier)茎的二氯甲烷提取物中分离出四个新的巴豆叶烷型二萜类化合物,即巴豆卡拉辛(A-D)(1-4),以及已知的巴豆叶素E。通过光谱方法确定了新化合物的结构,并通过单晶X射线数据分析进一步证实了化合物3的结构。