Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming 650224, China.
Molecules. 2018 Sep 12;23(9):2333. doi: 10.3390/molecules23092333.
The genus belongs to the Euphorbiaceae family, which comprises approximately 1300 species. Many species have been used as folk medicines. This review focuses on the chemical constituents from species and their relevant biological activities, covering the period from 2006 to 2018. A total of 399 new compounds, including 339 diterpenoids, were reported. Diterpenoids are characteristic components of the species. These isolated compounds exhibited a broad spectrum of bioactivities, including cytotoxic, anti-inflammatory, antifungal, acetylcholinesterase inhibitory, and neurite outgrowth-promoting properties. The present review provides a significant clue for further research of the chemical constituents from the species as potential medicines.
该属属于大戟科，约有 1300 种。许多种被用作民间药物。本综述重点介绍了 2006 年至 2018 年期间从 物种中分离得到的化学成分及其相关的生物活性。共报道了 399 种新化合物，包括 339 种二萜类化合物。二萜类化合物是 物种的特征成分。这些分离得到的化合物表现出广泛的生物活性，包括细胞毒性、抗炎、抗真菌、乙酰胆碱酯酶抑制和促进神经突生长活性。本综述为进一步研究 物种的化学成分作为潜在药物提供了重要线索。
