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眼眶骨外髓性粒细胞肉瘤:临床病理与免疫组织化学特征的相关性。

Orbital extra-medullary granulocytic sarcoma: clinicopathologic correlation with immunohistochemical features.

机构信息

Department of Oculoplastics and Ocular Oncology, Vasan Eye Care and L.V. Prasad Eye Institute, Hyderabad, India.

National Reporting Centre for Ophthalmic Pathology, Centre for Sight, Hyderabad and Department of Ophthalmic Pathology, L.V. Prasad Eye Institute, Hyderabad, India.

出版信息

Surv Ophthalmol. 2014 Mar-Apr;59(2):232-5. doi: 10.1016/j.survophthal.2013.06.004. Epub 2013 Oct 25.

DOI:10.1016/j.survophthal.2013.06.004
PMID:24556444
Abstract

Orbital granulocytic sarcoma (chloroma), a rare tumor of immature myeloid cells, has nonspecific clinical and radiological features that make it a diagnostic challenge. Light microscopy and confirmation by immunostaining aid in the diagnosis. Knowledge of this entity is important because early diagnosis and prompt treatment are associated with better prognosis. We report a series of 31 biopsy-proven orbital granulocytic sarcomas with their immunohistochemical features and review the literature.

摘要

眼眶粒细胞肉瘤(绿色瘤)是一种罕见的不成熟髓系细胞肿瘤,具有非特异性的临床和影像学特征,使其成为诊断难题。光镜检查和免疫组化染色的证实有助于诊断。了解该实体很重要,因为早期诊断和及时治疗与更好的预后相关。我们报告了 31 例经活检证实的眼眶粒细胞肉瘤及其免疫组化特征,并复习了文献。

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