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扩张型心肌病患者非心脏手术的麻醉管理

[Anesthetic management of patients with dilated cardiomyopathy undergoing non-cardiac surgery].

作者信息

Maekawa Takuji

机构信息

Department of Anesthesiology, Nagasaki University School of Medicine, Nagasaki 852-8501.

出版信息

Masui. 2014 Jan;63(1):22-30.

PMID:24558928
Abstract

There is little information on the perioperative management of patients with dilated cardiomyopathy (DCM) undergoing non-cardiac surgery. The presence of a history or signs of heart failure and un-diagnosed DCM preoperatively, may be associated with an increased risk during non-cardiac surgery. In these patients, preoperative assessment of LV function, including echocardiography, and assessment of an individual's capacity to perform a spectrum of common daily tasks may be recommended to quantify the severity of systolic function. It is important to prevent low cardiac output and arrhythmia for the perioperative management of patients with DCM. Sympathetic hyperactivity often causes atrial or ventricular tachyarrhythmia, which could worsen systemic hemodynamics in these patients. In particular, the prevention of life-threatening arrhythmia, such as, ventricular tachycardia or ventricular fibrillation is important. To prevent perioperative low output syndrome, inotropic support, using catecholamines or phosphodiesterase inhibitors with or without vasodilators should be performed under careful monitoring. It is desirable to use a pulmonary-artery catheter during moderate to high risk surgery, because the optimum level of left ventricular pre-load is very narrow in these patients. Every effort must be made to detect postoperative heart failure by careful monitoring, including PAC, and physical examination.

摘要

关于扩张型心肌病(DCM)患者接受非心脏手术的围手术期管理的信息很少。术前存在心力衰竭病史或体征以及未确诊的DCM,可能与非心脏手术期间风险增加有关。对于这些患者,可能建议进行术前左心室功能评估,包括超声心动图检查,以及评估个体执行一系列日常常见任务的能力,以量化收缩功能的严重程度。对于DCM患者的围手术期管理,预防低心输出量和心律失常很重要。交感神经过度活跃常导致房性或室性快速心律失常,这可能会使这些患者的全身血流动力学恶化。特别是,预防危及生命的心律失常,如室性心动过速或心室颤动很重要。为预防围手术期低输出量综合征,应在仔细监测下使用儿茶酚胺或磷酸二酯酶抑制剂,联合或不联合血管扩张剂进行正性肌力支持。在中高风险手术期间使用肺动脉导管是可取的,因为这些患者左心室前负荷的最佳水平非常窄。必须通过仔细监测,包括肺动脉导管监测和体格检查,尽一切努力检测术后心力衰竭。

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