Devetak Miha, Peršin Zdenka, Stana-Kleinschek Karin, Maver Uroš
1 CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia.
Microsc Microanal. 2014 Apr;20(2):561-5. doi: 10.1017/S1431927613014086. Epub 2014 Feb 24.
Polarization microscopy was used for evaluation of kinetics of diclofenac sorption in three different wound dressing materials. The sorption kinetics can be evaluated by radii change and intensity of the light traveling through the fiber. The most frequently used host materials for drugs in wound dressings are alginate, polyesters such as polyethylene terephthalate, and viscose. We studied sorption of diclofenac as an example drug. Effective, but rather simple in vitro simulation of diclofenac sorption gives insight into the applicability of the mentioned materials for development of wound healing materials.
偏光显微镜用于评估双氯芬酸在三种不同伤口敷料材料中的吸附动力学。吸附动力学可以通过纤维半径变化和透过纤维的光强度来评估。伤口敷料中最常用的药物宿主材料是藻酸盐、聚酯（如聚对苯二甲酸乙二酯）和粘胶纤维。我们以双氯芬酸为例研究了其吸附情况。对双氯芬酸吸附进行有效但相当简单的体外模拟，有助于深入了解上述材料在伤口愈合材料开发中的适用性。
