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接受质子放射治疗的儿童的非侵入性麻醉

Non-invasive anesthesia for children undergoing proton radiation therapy.

作者信息

Owusu-Agyemang Pascal, Grosshans David, Arunkumar Radha, Rebello Elizabeth, Popovich Shannon, Zavala Acsa, Williams Cynthia, Ruiz Javier, Hernandez Mike, Mahajan Anita, Porche Vivian

机构信息

Department of Anesthesiology & Perioperative Medicine, The University of Texas MD Anderson Cancer Center, United States.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, United States.

出版信息

Radiother Oncol. 2014 Apr;111(1):30-4. doi: 10.1016/j.radonc.2014.01.016. Epub 2014 Feb 20.

Abstract

BACKGROUND

Proton therapy is a newer modality of radiotherapy during which anesthesiologists face specific challenges related to the setup and duration of treatment sessions.

PURPOSE

Describe our anesthesia practice for children treated in a standalone proton therapy center, and report on complications encountered during anesthesia.

MATERIALS AND METHODS

A retrospective review of anesthetic records for patients ⩽18years of age treated with proton therapy at our institution between January 2006 and April 2013 was performed.

RESULTS

A total of 9328 anesthetics were administered to 340 children with a median age of 3.6years (range, 0.4-14.2). The median daily anesthesia time was 47min (range, 15-79). The average time between start of anesthesia to the start of radiotherapy was 7.2min (range, 1-83min). All patients received Total Intravenous Anesthesia (TIVA) with spontaneous ventilation, with 96.7% receiving supplemental oxygen by non-invasive methods. None required daily endotracheal intubation. Two episodes of bradycardia, and one episode each of; seizure, laryngospasm and bronchospasm were identified for a cumulative incidence of 0.05%.

CONCLUSIONS

In this large series of children undergoing proton therapy at a freestanding center, TIVA without daily endotracheal intubation provided a safe, efficient, and less invasive option of anesthetic care.

摘要

背景

质子治疗是一种较新的放射治疗方式,在此过程中麻醉医生面临与治疗设置和疗程持续时间相关的特定挑战。

目的

描述我们在独立质子治疗中心对儿童进行麻醉的实践,并报告麻醉期间遇到的并发症。

材料与方法

对2006年1月至2013年4月期间在本机构接受质子治疗的18岁及以下患者的麻醉记录进行回顾性研究。

结果

共对340名儿童实施了9328次麻醉,中位年龄为3.6岁(范围0.4 - 14.2岁)。每日中位麻醉时间为47分钟(范围15 - 79分钟)。从开始麻醉到开始放疗的平均时间为7.2分钟(范围1 - 83分钟)。所有患者均接受全凭静脉麻醉(TIVA)并自主通气,96.7%的患者通过无创方法接受补充氧气。无人需要每日进行气管插管。发现两例心动过缓,以及各一例癫痫、喉痉挛和支气管痉挛,累积发生率为0.05%。

结论

在这个独立中心接受质子治疗的大量儿童系列中,无需每日气管插管的全凭静脉麻醉提供了一种安全、高效且侵入性较小的麻醉护理选择。

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