Aix Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, 13005, Marseille, France,
Curr Infect Dis Rep. 2014 Mar;16(3):394. doi: 10.1007/s11908-014-0394-0.
Most cases of rabies in travelers are associated with dog bites and occur in adults who are commonly migrants. The incidence of injuries to travelers caused by potentially rabid animals is approximately 0.4 % per month of stay. Dogs account for 51 % of cases, but nonhuman primates are the leading animals responsible for injuries in travelers returning from Southeast Asia. Travel to Southeast Asia, India and North Africa, young age, and traveling for tourism are risk factors for potential exposure. More than 70 % of travelers are not immunized prior to departing and do not receive adequate care when injured. The intradermal vaccination route has been proven economical, safe and immunogenic in travelers. The immunity provided by the three-dose series is long-lasting and should be considered an investment for future travel. Abbreviated schedules may be used for last-minute travelers.
大多数旅行者感染狂犬病与狗咬伤有关,且多发生于成年人,这些成年人通常是移民。旅行者因可能携带狂犬病毒的动物而受伤的发生率约为逗留期间每月 0.4%。狗占病例的 51%,但从东南亚返回的旅行者受伤的主要动物是灵长类动物。前往东南亚、印度和北非、年龄较小和旅游出行是潜在暴露的风险因素。超过 70%的旅行者在出发前未接种疫苗,受伤后也未得到充分的护理。皮内疫苗接种途径已被证明在旅行者中经济、安全且具有免疫原性。三剂系列疫苗提供的免疫力持久,应被视为未来旅行的一项投资。对于临时决定出行的旅行者,可以使用简化的时间表。