Panda Amrita Kumari, Bisht Satpal Singh, DeMondal Surajit, Senthil Kumar N, Gurusubramanian G, Panigrahi Ashok Kumar
Department of Biotechnology, Mizoram University, Aizwal, 796004, Mizoram, India,
Antonie Van Leeuwenhoek. 2014 Apr;105(4):623-39. doi: 10.1007/s10482-013-0099-7. Epub 2014 Feb 22.
The significance of Brevibacillus has been documented scientifically in the published literature and commercially in heterologous recombinant protein catalogs. Brevibacillus is one of the most widespread genera of Gram-positive bacteria, recorded from the diverse environmental habitats. The high growth rate, better transformation efficiency by electroporation, availability of shuttle vectors, production of negligible amount of extracellular protease, and the constitutive expression of heterologous proteins make some strains of this genus excellent laboratory models. Regarding biotechnological applications, this genus continues to be a source of various enzymes of great biotechnological interest due to their ability to biodegrade low density polyethylene, ability to act as a candidate bio-control agent, and more recently acknowledged as a tool for the overexpression. This article reviews the properties of Brevibacillus spp. as better biological tools with varied applications.
短短芽孢杆菌属的重要性已在科学文献中得到记载，并且在商业上的异源重组蛋白目录中也有体现。短短芽孢杆菌属是革兰氏阳性菌中分布最广泛的属之一，在各种不同的环境栖息地中均有记录。该属的一些菌株生长速度快、电穿孔转化效率高、有穿梭载体可用、细胞外蛋白酶产量可忽略不计以及异源蛋白组成型表达，使其成为优秀的实验室模型。在生物技术应用方面，由于该属具有生物降解低密度聚乙烯的能力、可作为候选生物防治剂以及最近被认可为过表达工具，它仍然是具有重大生物技术意义的各种酶的来源。本文综述了短短芽孢杆菌属作为具有多种应用的更好生物工具的特性。
