Texas A&M University, College Station, TX, USA.
Eur J Nutr. 2014 Apr;53 Suppl 1(Suppl 1):1-9. doi: 10.1007/s00394-014-0666-3.
Bioactives can be defined as: "Constituents in foods or dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status" (Office of Disease Prevention and Health Promotion, Office of Public Health and Science, Department of Health and Human Services in Fed Reg 69:55821-55822, 2004). Although traditional nutrients, such as vitamins, minerals, protein, essential fatty acids and essential amino acids, have dietary reference intake (DRI) values, there is no such evaluative process for bioactives. For certain classes of bioactives, substantial scientific evidence exists to validate a relationship between their intake and enhanced health conditions or reduced risk of disease. In addition, the study of bioactives and their relationship to disease risk is a growing area of research supported by government, academic institutions, and food and supplement manufacturers. Importantly, consumers are purchasing foods containing bioactives, yet there is no evaluative process in place to let the public know how strong the science is behind the benefits or the quantitative amounts needed to achieve these beneficial health effects. This conference, Bioactives: Qualitative Nutrient Reference Values for Life-stage Groups?, explored why it is important to have a DRI-like process for bioactives and challenges for establishing such a process.
“存在于食物或膳食补充剂中的成分，除了满足人类基本营养需求所需的成分外，这些成分负责改变健康状况”（疾病预防和健康促进办公室，公共卫生和科学办公室，卫生和人类服务部，在 Fed Reg 69:55821-55822，2004 年）。尽管传统营养素，如维生素、矿物质、蛋白质、必需脂肪酸和必需氨基酸，具有膳食参考摄入量（DRI）值，但对于生物活性物质没有这样的评估过程。对于某些类别的生物活性物质，有大量的科学证据证明它们的摄入量与增强的健康状况或降低疾病风险之间存在关联。此外，生物活性物质及其与疾病风险的关系研究是一个日益增长的研究领域，得到了政府、学术机构、食品和补充剂制造商的支持。重要的是，消费者正在购买含有生物活性物质的食品，但没有评估过程让公众了解背后的科学依据有多强大，或者需要摄入多少才能达到这些有益的健康效果。本次会议“生物活性物质：生命阶段群体的定性营养素参考值？”探讨了为什么为生物活性物质建立类似于 DRI 的过程很重要，以及建立这样一个过程所面临的挑战。
