Hjelmgaard Thomas, Roy Olivier, Nauton Lionel, El-Ghozzi Malika, Avignant Daniel, Didierjean Claude, Taillefumier Claude, Faure Sophie
Department of Chemistry, Section for Chemical Biology and Nanoscience, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark.
Chem Commun (Camb). 2014 Apr 7;50(27):3564-7. doi: 10.1039/c4cc00821a. Epub 2014 Feb 24.
The head-to-tail conversion of linear arylopeptoids (oligomeric N-substituted aminomethyl benzamides) into the derived novel macrocycles has enabled the first X-ray structures of arylopeptoid constructs and the identification of well-defined architectures in solution.
线性芳基肽模拟物(低聚N-取代氨基甲基苯甲酰胺)向衍生的新型大环化合物的头对尾转化,使得首次获得芳基肽模拟物结构的X射线晶体结构,并确定了溶液中明确的结构。