Fischer P R, Reta B B
Evangelical Medical Center, Nyankunde, Zaire.
Ann Trop Paediatr. 1988 Jun;8(2):85-6. doi: 10.1080/02724936.1988.11748545.
With the emergence of chlamydia as a major cause of neonatal conjunctivitis, silver nitrate is no longer the prophylactic agent of choice in many parts of the world. We studied 450 consecutive newborns in north-eastern Zaire in an effort to determine which of two agents provided the most effective prophylaxis. None of 236 newborns treated at birth with 1% silver nitrate and none of 123 treated with 1% tetracycline was found to develop conjunctivitis. Three of 91 "forgotten" babies developed gonococcal conjunctivitis. Nurses, thinking tetracycline was "messy", tended to "forget" to treat babies for whom tetracycline was prescribed. The use of silver nitrate still provides adequate prophylaxis in Zaire. Potential changes in the prophylactic regimen would need to take the perceptions of health care workers into account.
随着衣原体成为新生儿结膜炎的主要病因，硝酸银在世界许多地区已不再是首选的预防药物。我们对扎伊尔东北部的450名连续新生儿进行了研究，以确定两种药物中哪一种提供了最有效的预防措施。出生时用1%硝酸银治疗的236名新生儿中没有发现结膜炎病例，用1%四环素治疗的123名新生儿中也没有发现结膜炎病例。91名“被遗忘”的婴儿中有3名患上了淋菌性结膜炎。护士们认为四环素“不干净”，往往会“忘记”给开了四环素的婴儿进行治疗。在扎伊尔，使用硝酸银仍然可以提供充分的预防措施。预防性治疗方案的潜在变化需要考虑到医护人员的观念。
