Kobayashi Tsukane, Yagami Akiko, Suzuki Kayoko, Yoshikawa Tetsushi, Matsunaga Kayoko
Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Department of Dermatology, Kariya Toyota General Hospital, Kariya, Japan.
Case Rep Dermatol. 2014 Jan 8;6(1):5-9. doi: 10.1159/000358005. eCollection 2014 Jan.
Concurrent reactivation of herpes simplex and varicella zoster viruses is rare. Here, we describe the case of an elderly patient with herpes labialis and herpes zoster manifesting as a right-side facial eruption with vesicles and crusting. The loop-mediated isothermal amplification (LAMP) assay demonstrated the presence of both herpes simplex virus type 1 and varicella zoster virus in swab samples taken from the face, which was confirmed by real-time PCR, suggesting concurrent reactivation of both viruses. The use of the LAMP assay in the present case indicates its usefulness in the diagnosis of atypical herpes infections.
单纯疱疹病毒和水痘带状疱疹病毒的同时再激活很少见。在此，我们描述了一例老年患者，其患有唇疱疹和带状疱疹，表现为右侧面部出现水疱和结痂的皮疹。环介导等温扩增（LAMP）检测显示，从面部采集的拭子样本中同时存在1型单纯疱疹病毒和水痘带状疱疹病毒，实时PCR证实了这一点，提示两种病毒同时再激活。本病例中LAMP检测的应用表明其在非典型疱疹感染诊断中的有用性。
