Javadzadeh Shahshahani H, Vaziri M, Mansouri F
Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Medical Doctor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Yazd, Iran.
Iran J Ped Hematol Oncol. 2013;3(3):119-24. Epub 2013 Jul 22.
Increasing blood supply safety is one of the most important goals of blood services in the world. In this study, we reviewed the prevalence rate and the trends of three main infections in whole blood donations and strategies for improving blood safety in Yazd blood transfusion center, Iran.
In this cross sectional study, data on hepatitis B, C and HIV infection were extracted from Iranian Donor Database of blood donation from 2004 to 2010 in Yazd province. All donors with positive confirmatory test were included. The data was analyzed by SPSS software due to demographic factors.
The prevalence rate of hepatitis B, C and HIV infection decreased during these years (From 0.37%, 0.14% and 0 percent in 2004 to 0.14%, 0.05% and 0 in 2010, respectively). Both hepatitis B and C infections were significantly more in first-time blood donors with BSc or BA educational level. The prevalence rate of hepatitis B was significantly higher in donors with less than 20 year-old and female donors. The prevalence rate of hepatitis C was higherin30-39 age group (P-value= 0.014).
The results showed that the strategies used for improving blood safety were efficient. Increasing public knowledge on blood-borne infections and their routes of transmission, importance of donating blood only by healthy donors are necessary to have a safe blood supply in future.
提高血液供应安全性是全球血液服务最重要的目标之一。在本研究中,我们回顾了伊朗亚兹德输血中心全血捐献中三种主要感染的流行率和趋势,以及提高血液安全性的策略。
在这项横断面研究中,从2004年至2010年亚兹德省伊朗献血者数据库中提取了乙肝、丙肝和艾滋病毒感染的数据。所有确诊检测呈阳性的献血者均被纳入。因人口统计学因素,数据由SPSS软件进行分析。
这些年乙肝、丙肝和艾滋病毒感染的流行率有所下降(分别从2004年的0.37%、0.14%和0%降至2010年的0.14%、0.05%和0)。乙肝和丙肝感染在拥有理学学士或文学学士学位的首次献血者中显著更多。乙肝感染的流行率在年龄小于20岁的献血者和女性献血者中显著更高。丙肝感染的流行率在30 - 39岁年龄组中更高(P值 = 0.014)。
结果表明用于提高血液安全性的策略是有效的。增加公众对血源性感染及其传播途径的认识,以及仅由健康献血者献血的重要性,对于未来获得安全的血液供应是必要的。