Zalina A Z, Lee V C, Kandiah M
Department of Nutrition & Dietetics, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Malays J Nutr. 2012 Aug;18(2):255-64.
The objective of this study was to determine the relationship between nutritional status, physical activity and quality of life among gastrointestinal cancer survivors.
A cross-sectional study was conducted among gastrointestinal cancer survivors attending the oncology outpatient clinic in Hospital Selayang, Malaysia.
A total of 70 gastrointestinal cancer survivors with a mean age of 52.54 +/- 14.59 years (95% CI: 47.48 - 57.60) were included in this study. Results showed that 40% of the patients were classified as having low physical activity. The mean Patient Generated Subjective Global Assessment (PGSGA) score was 10.27 +/- 7.36 (95% CI: 8.23-12.31) and nearly half the patients (48.6%) were identified as severely malnourished (Stage C). Mean Gastrointestinal Quality of Life Index (GQLFI) score was 103.57 +/- 23.85 (95% CI: 92.94-114.20), and about 24.3% of the patients were classified as having a low quality of life. Pearson's correlation test showed a highly significant negative relationship between nutritional status and quality of life (r = -0.661, p<0.001) indicating the better the nutritional status (low total mean score of PGSGA), the better the quality of life of the survivors (high total mean score of GQLFI). There was a significant negative relationship between physical activity level and nutritional status score (r = -0.309, p<0.01), indicating the higher the physical activity level of the patients (high MET-min/week), the better their nutritional status (low total mean score of PGSGA).
This study shows a significant relationship between nutritional status, physical activity and quality of life among gastrointestinal cancer survivors. Those low in nutritional status have a low quality of life while survivors with higher nutritional status have a better quality of life.
本研究的目的是确定胃肠道癌症幸存者的营养状况、身体活动与生活质量之间的关系。
对在马来西亚士拉央医院肿瘤门诊就诊的胃肠道癌症幸存者进行了一项横断面研究。
本研究共纳入70名胃肠道癌症幸存者，平均年龄为52.54±14.59岁（95%置信区间：47.48 - 57.60）。结果显示，40%的患者被归类为身体活动水平低。患者主观全面评定法（PGSGA）的平均得分是10.27±7.36（95%置信区间：8.23 - 12.31），近一半的患者（48.6%）被确定为严重营养不良（C期）。胃肠道生活质量指数（GQLFI）的平均得分是103.57±23.85（95%置信区间：92.94 - 114.20），约24.3%的患者被归类为生活质量低。Pearson相关性检验显示营养状况与生活质量之间存在高度显著的负相关（r = -0.661，p<0.001），表明营养状况越好（PGSGA总平均分越低），幸存者的生活质量越好（GQLFI总平均分越高）。身体活动水平与营养状况评分之间存在显著的负相关（r = -0.309，p<0.01），表明患者的身体活动水平越高（每周代谢当量分钟数越高），其营养状况越好（PGSGA总平均分越低）。
本研究表明胃肠道癌症幸存者的营养状况、身体活动与生活质量之间存在显著关系。营养状况差的患者生活质量低，而营养状况较好的幸存者生活质量更好。
