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印度土产水果余甘子的抗糖尿病作用:活性成分和作用方式。

Anti-diabetic effects of the Indian indigenous fruit Emblica officinalis Gaertn: active constituents and modes of action.

机构信息

Research and Development cell, Department of Research, Father Muller Medical College, Kankanady, Mangalore, Karnataka, India 575002.

出版信息

Food Funct. 2014 Apr;5(4):635-44. doi: 10.1039/c3fo60366k.

DOI:10.1039/c3fo60366k
PMID:24577384
Abstract

Dietary constituents are shown to play an important role in the development of diabetes. Studies have shown that the fruits of Emblica officinalis Gaertn or Phyllanthus emblica Linn, colloquially known as Indian gooseberry or amla and/or some of its important constituents (including gallic acid, gallotanin, ellagic acid and corilagin), possess anti-diabetic effects through their antioxidant and free radical scavenging properties. Amla has also been reported to prevent/reduce hyperglycemia, cardiac complications, diabetic nephropathy, neuropathy, cataractogenesis and protein wasting. However, clinical trial data with human subjects are limited and preliminary. For the first time this review summarizes the anti-diabetic affects of amla and also addresses the mechanisms mediating these properties.

摘要

饮食成分被证明在糖尿病的发展中起着重要作用。研究表明,余甘子(Phyllanthus emblica Linn)或余甘果(Emblica officinalis Gaertn)的果实,俗称印度醋栗或余甘子,以及其一些重要成分(包括没食子酸、鞣花单宁、鞣花酸和柯里拉京),通过其抗氧化和清除自由基的特性具有抗糖尿病作用。余甘子也被报道可以预防/减少高血糖、心脏并发症、糖尿病肾病、神经病、白内障形成和蛋白质流失。然而,有人类受试者的临床试验数据有限且初步。这篇综述首次总结了余甘子的抗糖尿病作用,并探讨了介导这些特性的机制。

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