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水果:植物化学、传统用途、生物活性成分和药理活性综述。

The Fruits: A Review on Phytochemistry Traditional Uses, Bioactive Composition and Pharmacological Activities.

机构信息

Institute of Pharmaceutical Research GLA University, Mathura Uttar Pradesh, 281406, India.

Alembic Pharmaceutical, Karol Bagh, Central Delhi, India.

出版信息

Curr Top Med Chem. 2024;24(22):1917-1939. doi: 10.2174/0115680266321320240708060327.

DOI:10.2174/0115680266321320240708060327
PMID:39069705
Abstract

, popularly mentioned as amla or Indian gooseberry, has attracted a lot of interest lately because of its varied phytochemical makeup and related pharmacological properties. The phytochemistry, historical applications, bioactive makeup, and pharmacological properties of fruits are all summarised in this paper. This review emphasises the rich phytochemical profile of , which contains flavonoids, tannins, alkaloids, and polyphenolic chemicals, through a thorough assessment of the literature. Furthermore, the historical value of as a therapeutic agent for a variety of health issues is shown by its traditional applications in numerous indigenous medical systems. The bioactive makeup of fruits, especially its high polyphenol and vitamin C content, is responsible for its hepatoprotective, antioxidant, and anti-inflammatory qualities. Moreover, new pharmacological research has clarified its potential for the cure of neurological illnesses, tumor, diabetes, and cardiovascular diseases. In order to shed light on the pharmacological properties of fruits and suggest future avenues for study, this review compiles the body of scientific data that is already accessible. All things considered, shows great promise as a natural resource with significant applications in complementary and alternative medicine and pharmacological research.

摘要

, 俗称印度醋栗或 amla,由于其多样的植物化学成分和相关的药理学特性,最近引起了广泛关注。本文总结了 的植物化学、历史应用、生物活性成分和药理学特性。通过对文献的全面评估,本文强调了 丰富的植物化学成分,其中包括类黄酮、单宁、生物碱和多酚类化合物。此外,通过众多本土医疗体系中对 的传统应用,展示了其作为治疗各种健康问题的治疗剂的历史价值。 水果的生物活性成分,特别是其高多酚和维生素 C 含量,使其具有保肝、抗氧化和抗炎作用。此外,新的药理学研究阐明了其在治疗神经疾病、肿瘤、糖尿病和心血管疾病方面的潜力。为了阐明 水果的药理学特性,并为未来的研究提出建议,本综述汇集了现有的科学数据。综上所述, 作为一种具有重要补充和替代医学及药理学研究应用潜力的天然资源,具有广阔的前景。

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本文引用的文献

1
Traditional uses, bioactive composition, pharmacology, and toxicology of Phyllanthus emblica fruits: A comprehensive review.余甘子的传统用途、生物活性成分、药理学和毒理学:全面综述。
J Ethnopharmacol. 2022 Jan 10;282:114570. doi: 10.1016/j.jep.2021.114570. Epub 2021 Sep 2.
2
Nephroprotective effect of Emblica officinalis fruit extract against malachite green toxicity in piscine model: Ultrastructure and oxidative stress study.余甘子果提取物对鱼类模型中孔雀石绿毒性的肾脏保护作用:超微结构和氧化应激研究。
Microsc Res Tech. 2021 Aug;84(8):1911-1919. doi: 10.1002/jemt.23747. Epub 2021 Mar 9.
3
Bioactivity-guided isolation of anti-inflammatory components from .
从……中进行生物活性导向的抗炎成分分离。 (原句不完整,此为补充完整意思后的译文)
Food Sci Nutr. 2020 Apr 22;8(6):2670-2679. doi: 10.1002/fsn3.1553. eCollection 2020 Jun.
4
Emblicanin rich extract encapsulated double emulsion: controlled release of bioactive during phagocytosis and in vitro digestion.富含余甘子素的提取物包封双乳液:吞噬作用和体外消化过程中生物活性成分的控释
J Food Sci Technol. 2020 Apr;57(4):1371-1381. doi: 10.1007/s13197-019-04171-0. Epub 2019 Nov 16.
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Bioactive constituents of Emblica officinalis overcome oxidative stress in mammalian cells by inhibiting hyperoxidation of peroxiredoxins.余甘子的生物活性成分通过抑制过氧化物酶的过度氧化来克服哺乳动物细胞中的氧化应激。
J Food Biochem. 2020 Feb;44(2):e13115. doi: 10.1111/jfbc.13115. Epub 2019 Dec 10.
6
Standardized Emblica officinalis fruit extract inhibited the activities of α-amylase, α-glucosidase, and dipeptidyl peptidase-4 and displayed antioxidant potential.标准化余甘子果提取物抑制α-淀粉酶、α-葡萄糖苷酶和二肽基肽酶-4 的活性,并显示出抗氧化潜力。
J Sci Food Agric. 2020 Jan 30;100(2):509-516. doi: 10.1002/jsfa.10020. Epub 2019 Nov 13.
7
Phytofabrication of Selenium Nanoparticles From Fruit Extract and Exploring Its Biopotential Applications: Antioxidant, Antimicrobial, and Biocompatibility.利用水果提取物进行硒纳米颗粒的植物合成及其生物潜力应用探索:抗氧化、抗菌和生物相容性
Front Microbiol. 2019 Apr 30;10:931. doi: 10.3389/fmicb.2019.00931. eCollection 2019.
8
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Phytomedicine. 2020 Jul 15;73:152906. doi: 10.1016/j.phymed.2019.152906. Epub 2019 Apr 1.
9
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