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金莲花抗炎活性部位及化合物的活性导向研究

Activity directed investigation on anti-inflammatory fractions and compounds from flowers of Trollius chinensis.

作者信息

Wang Rufeng, Wu Xiuwen, Liu Lijia, An Yannan

机构信息

School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.

School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR Chin.

出版信息

Pak J Pharm Sci. 2014 Mar;27(2):285-8.

PMID:24577916
Abstract

The flower of Trollius chinensis Bunge is used as an anti-inflammatory drug to treat upper respiratory tract infection, pharyngitis, tonsillitis, and bronchitis. In order to identify the active components, the activity-screen directed compound isolation was carried out, leading to the identification of the major active fraction and 4 compounds thereof. As a result, flavonoids and phenolics were demonstrated to be the major anti-inflammatory components.

摘要

金莲花被用作抗炎药物来治疗上呼吸道感染、咽炎、扁桃体炎和支气管炎。为了鉴定其活性成分,开展了活性筛选导向的化合物分离工作,从而鉴定出主要活性部位及其4种化合物。结果表明,黄酮类和酚类是主要的抗炎成分。

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