Okada Tomu, Fujitsu Kazuhiko, Ichikawa Teruo, Mukaihara Shigeo, Miyahara Kousuke, Tanino Shin, Uriu Yasuhiro, Sakamoto Takahiro, Hataoka Syunsuke, Kubota Jyunichi, Suzuki Kouji, Niino Hitoshi, Yagishita Saburou
Department of Neurosurgery and.
Ultrastruct Pathol. 2014 Aug;38(4):290-4. doi: 10.3109/01913123.2014.888115. Epub 2014 Feb 28.
Fibrous or transitional meningioma and solitary fibrous tumor (SFT) are frequently difficult to differentiate from each other on the basis of histopathology. It is extremely unusual for a meningioma to exhibit diffuse, strongly positive immunoreactivity for cluster of differentiation 34 (CD34), and this has never been previously reported from a histopathological specimen. A patient with transitional meningioma that exhibited strongly positive for CD34, which has been regarded as characteristic of SFT and is considered to be useful for distinguishing the latter from meningioma, is reported.
纤维型或过渡型脑膜瘤与孤立性纤维性肿瘤（SFT）在组织病理学基础上常常难以相互区分。脑膜瘤表现出弥漫性、对分化簇34（CD34）呈强阳性免疫反应极为罕见，且此前从未有过组织病理学标本的相关报道。本文报告了一例过渡型脑膜瘤患者，该肿瘤对CD34呈强阳性，而CD34一直被视为SFT的特征，被认为有助于将SFT与脑膜瘤区分开来。
