Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.
Reprod Health. 2014 Feb 28;11(1):19. doi: 10.1186/1742-4755-11-19.
To compare the proportion of women with self-reported depression and anxiety symptoms at four months postpartum between mothers of singletons who conceived spontaneously and mothers who conceived with the aid of fertility treatment.
The sample used for this study was drawn from The "All Our Babies Study", a community-based prospective cohort of 1654 pregnant women who received prenatal care in Calgary, Alberta. This analysis included women utilizing fertility treatment and a randomly selected 1:2 comparison group. The data was collected via three questionnaires, two of which were mailed to the participants during pregnancy and one at four months postpartum. Symptoms of depression and anxiety at four months postpartum were measured using the Edinburg Postnatal Depression Scale and the Spielberger State Anxiety Inventory. Secondary outcomes of parenting morale and perceived stress were also evaluated. Descriptive statistics were used to characterize the population. Chi square tests and in cases of small cell sizes, Fisher Exact Tests were used to assess differences in postpartum mental health symptomatology between groups.
Seventy-six participants (5.9%) conceived using a form of fertility treatment. At four months postpartum, no significant differences were observed in the proportions reporting excessive depression symptoms (2.6% vs. 5.3%, p = 0.50), anxiety (8.1% vs. 16.9%, p = 0.08) or high perceived stress scores (7.9% vs. 13.3%, p = 0.23). Women who conceived with fertility treatment were less likely to score low on parenting morale compared to women who conceived spontaneously and this was particularly evident in primiparous women (12.5% vs. 33.8%, p = 0.01). There were no group differences in proportions reporting low parenting morale in multiparous women.
This study suggests that at four months postpartum, the proportion of women who experience elevated symptoms of depression, anxiety or perceived stress do not differ between mothers who conceive using fertility treatment and those who conceive spontaneously. Parenting morale at four months postpartum is significantly lower in primiparous mothers conceiving spontaneously compared to those who conceive with fertility treatment.
比较自然受孕和辅助生育受孕的单胎母亲在产后四个月时报告有抑郁和焦虑症状的女性比例。
本研究的样本来自于“所有婴儿研究”，这是一个基于社区的前瞻性队列研究，共有 1654 名在艾伯塔省卡尔加里接受产前护理的孕妇。该分析包括使用生育治疗的女性和随机选择的 1:2 对照组。数据通过三个问卷收集，其中两个在怀孕期间邮寄给参与者，一个在产后四个月时邮寄。产后四个月时的抑郁和焦虑症状使用爱丁堡产后抑郁量表和斯皮尔伯格状态焦虑量表进行测量。还评估了次要结局，包括育儿士气和感知压力。使用描述性统计来描述人群特征。使用卡方检验和小单元格情况下的 Fisher 精确检验来评估两组之间产后心理健康症状的差异。
76 名参与者（5.9%）使用某种形式的生育治疗受孕。产后四个月时，报告有过多抑郁症状的比例（2.6% vs. 5.3%，p=0.50）、焦虑症状（8.1% vs. 16.9%，p=0.08）或高感知压力评分（7.9% vs. 13.3%，p=0.23）的比例无显著差异。与自然受孕的女性相比，使用生育治疗受孕的女性育儿士气评分较低，这在初产妇中尤为明显（12.5% vs. 33.8%，p=0.01）。在多产妇中，两组在报告低育儿士气的比例上没有差异。
本研究表明，在产后四个月时，使用生育治疗受孕和自然受孕的母亲经历抑郁、焦虑或感知压力等症状加重的比例没有差异。与自然受孕的初产妇相比，使用生育治疗受孕的初产妇产后四个月时的育儿士气明显较低。
