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激光辅助上皮下角膜切除术矫正近视散光时眼内散光的影响。

Influence of intraocular astigmatism on the correction of myopic astigmatism by laser-assisted subepithelial keratectomy.

机构信息

From the Department of Ophthalmology (Qian, Huang, Chu, Zhou), Eye and ENT Hospital, Fudan University, and the Key Laboratory of Myopia of State Health Ministry (Qian, Huang, Chu, Zhou), Shanghai, China; the Department of Surgery (Olszewski), Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.

From the Department of Ophthalmology (Qian, Huang, Chu, Zhou), Eye and ENT Hospital, Fudan University, and the Key Laboratory of Myopia of State Health Ministry (Qian, Huang, Chu, Zhou), Shanghai, China; the Department of Surgery (Olszewski), Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.

出版信息

J Cataract Refract Surg. 2014 Apr;40(4):558-63. doi: 10.1016/j.jcrs.2013.09.017. Epub 2014 Feb 26.

Abstract

PURPOSE

To assess the influence of the origin of astigmatism on the correction of myopic astigmatism by laser-assisted subepithelial keratectomy (LASEK).

SETTING

Ophthalmology Department, Eye and ENT Hospital, Shanghai, China.

DESIGN

Prospective study.

METHODS

Patients having LASEK to correct myopia or myopic astigmatism were divided into 2 groups according to their ocular residual astigmatism (ORA). Patients were examined preoperatively and 1 and 3 months postoperatively. The efficacy of LASEK was compared between those with and those without a significant amount of intraocular astigmatism.

RESULTS

The study comprised 54 eyes of 54 patients. The mean index of success (ratio of magnitude of remaining uncorrected astigmatism to that of initial preoperative astigmatism) in the high ORA group (n=21) and low ORA group (n=33) was 0.85 and 0.48, respectively, 1 month after surgery (t=2.17, P=.04) and 0.88 and 0.32, respectively, 3 months after surgery (t=2.18, P=.04). The Zernike coefficient of horizontal coma, Z(3,+1), increased more after surgery in the high ORA group than in the low ORA group (1 month versus preoperative, t=2.32, P=.024; 3 months versus preoperative, t=2.07, P=.048).

CONCLUSIONS

Nine percent and 2% of the eyes had minimal corneal haze at 1 month and 3 months, respectively. Laser-assisted subepithelial keratectomy was less effective in correcting myopic astigmatism when astigmatism was mainly located at the internal optics. Horizontal coma increased more after LASEK in patients with higher ORA.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

评估激光辅助上皮下角膜切除术(LASEK)治疗近视性散光时散光来源对散光矫正的影响。

地点

中国上海,眼耳鼻喉科医院眼科。

设计

前瞻性研究。

方法

根据眼内残余散光(ORA)将接受 LASEK 治疗近视或近视散光的患者分为 2 组。术前和术后 1、3 个月对患者进行检查。比较有大量眼内散光和无大量眼内散光患者的 LASEK 疗效。

结果

该研究共纳入 54 例(54 只眼)患者。高 ORA 组(n=21)和低 ORA 组(n=33)术后 1 个月和 3 个月的平均指数成功率(残余未矫正散光与初始术前散光的比值)分别为 0.85 和 0.48(t=2.17,P=.04)和 0.88 和 0.32(t=2.18,P=.04)。术后高 ORA 组的水平彗差 Zernike 系数 Z(3,+1)增加较明显(术后 1 个月与术前相比,t=2.32,P=.024;术后 3 个月与术前相比,t=2.07,P=.048)。

结论

术后 1 个月和 3 个月分别有 9%和 2%的眼出现轻微角膜混浊。当散光主要位于眼内光学区时,LASEK 矫正近视性散光的效果较差。高 ORA 患者 LASEK 术后水平彗差增加较明显。

利益冲突

无作者在提到的任何材料或方法中存在财务或所有权利益。

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