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一项试点研究:使用MEL 90的三重A模式进行准分子上皮下角膜磨镶术治疗轻度和中度近视。

A pilot study: LASEK with the Triple-A profile of a MEL 90 for mild and moderate myopia.

作者信息

Chen Yingjun, Yang Dong, Han Tian, Xu Haipeng, Li Meiyan, Zhou Xingtao

机构信息

Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.

Carl Zeiss Meditec AG, Shanghai, China.

出版信息

BMC Ophthalmol. 2017 Jun 23;17(1):98. doi: 10.1186/s12886-017-0493-4.

Abstract

BACKGROUND

To investigate the visual and refractive outcomes in patients with mild to moderate myopia after laser-assisted subepithelial keratectomy (LASEK) using the 500 Hz pulse rate of the Triple-A profile.

METHODS

Thirty-six eyes of 20 patients (mean age, 27.5 ± 4.6 years) were included in this prospective, consecutive study. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corneal topography, and corneal aberrations were measured preoperatively and 1 day, 1 week, 1, 3 and 6 months post-operation.

RESULTS

At 1 week after surgery, UDVA was better than or equal to 20/25 in all eyes. At postoperative 6 months, the efficacy and safety index was 1.05 ± 0.13 and 1.12 ± 0.15, respectively; all eyes had a UDVA of 20/20 or better, and no eyes showed a loss in CDVA; 100% of the eyes were within ±1.00 D of the attempted spherical equivalent (SE) correction.

CONCLUSION

The postoperative results indicate that using the Triple-A ablation profile of the MEL 90 excimer laser with a 500 Hz pulse rate is a safe, efficient, and predictable method to correct mild to moderate myopia.

摘要

背景

使用500Hz脉冲频率的Triple-A模式,研究准分子激光上皮瓣下角膜磨镶术(LASEK)治疗轻中度近视患者的视觉和屈光效果。

方法

本前瞻性连续研究纳入了20例患者(平均年龄27.5±4.6岁)的36只眼。术前及术后1天、1周、1、3和6个月测量裸眼远视力(UDVA)、矫正远视力(CDVA)、角膜地形图和角膜像差。

结果

术后1周时,所有眼的UDVA均优于或等于20/25。术后6个月时,有效性和安全性指数分别为1.05±0.13和1.12±0.15;所有眼的UDVA均达到20/20或更好,且无眼CDVA下降;100%的眼在预期等效球镜度(SE)矫正的±1.00D范围内。

结论

术后结果表明,使用MEL 90准分子激光的Triple-A消融模式和500Hz脉冲频率是一种安全、有效且可预测的矫正轻中度近视的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b45/5481973/260a93510a28/12886_2017_493_Fig1_HTML.jpg

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