Aydın Pinar Cetinay, Koybasi Gulperi Putgul, Sert Engin, Mete Levent, Oyekcin Demet Gulec
Department of Psychiatry Clinic, Bakirkoy Mental Health Research and Training Hospital, Postcode: 34140Bakirkoy Istanbul, Turkey.
Menemen State Hospital Izmır, Turkey.
Compr Psychiatry. 2014 May;55(4):904-11. doi: 10.1016/j.comppsych.2014.01.005. Epub 2014 Jan 21.
There are concurrently with different results of studies about cognitive functions of Obsessive-Compulsive Disorder (OCD), impairment in non-verbal memory and executive functioning in OCD, has shown consistent results in several studies. In this study, 62 OCD patients and 40 healthy controls were participated. Firstly, cognitive functions of OCD group and healthy control group were compared in terms of scores in Stroop Test, Wisconsin Cart Sorting Test (WCST), Auditory Consonant Trigram Test (ACTT), Controlled Word Association Test (CWAT), Rey Auditory Verbal Learning Test (RAVLT), Digit Span Test (DST). And then, two patient groups of OCD patients (patients with autogenous obsessions and patients with reactive obsessions) were compared in terms of the scores of same tests, with a hypothesis that claims, cognitive functions of patients with autogenous obsessions, who shown schizotypal personality features and thought disorder in higher ratio, will show more impairment than cognitive functions of patients with reactive obsessions. Significant impairment was found in OCD patients in terms of Stroop test and WCST scores when compared to scores of healthy controls. There was no difference pointed out between cognitive functions of patients with autogenous obsessions and reactive obsessions. Due to limited number of patients with autogenous obsessions in current study, any future research with greater sample size will be helpful to explain the cognitive functions in OCD with autogenous and reactive obsessions.
关于强迫症(OCD)认知功能的研究结果各不相同,然而,强迫症患者在非言语记忆和执行功能方面的损害在多项研究中显示出一致的结果。在本研究中,62名强迫症患者和40名健康对照者参与其中。首先,比较了强迫症组和健康对照组在Stroop测试、威斯康星卡片分类测试(WCST)、听觉辅音连缀测试(ACTT)、受控词联想测试(CWAT)、雷伊听觉词语学习测试(RAVLT)、数字广度测试(DST)中的得分,以此来评估他们的认知功能。然后,比较了两组强迫症患者(原发性强迫观念患者和反应性强迫观念患者)在相同测试中的得分,研究假设认为,原发性强迫观念患者中具有分裂型人格特征和思维障碍的比例更高,其认知功能受损程度将比反应性强迫观念患者更严重。与健康对照组的得分相比,发现强迫症患者在Stroop测试和WCST得分方面存在显著损害。原发性强迫观念患者和反应性强迫观念患者的认知功能之间没有差异。由于本研究中原发性强迫观念患者数量有限,未来任何更大样本量的研究都将有助于解释原发性和反应性强迫观念患者的强迫症认知功能。