Yazdi-Ravandi Saeid, Shamsaei Farshid, Matinnia Nasrin, Shams Jamal, Moghimbeigi Abbas, Ghaleiha Ali, Ahmadpanah Mohammad
Behavioral Disorders and Substance Abuse Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Department of Nursing, Faculty of Basic Sciences, Hamadan Branch, Islamic Azad University, Hamadan, Iran.
Basic Clin Neurosci. 2018 Nov-Dec;9(6):448-457. doi: 10.32598/bcn.9.6.448. Epub 2018 Nov 1.
In recent studies, deficit in cognitive process has been investigated as one of the etiological hypotheses in a wide range of Obsessive-Compulsive Disorder (OCD). This research aimed to compare cognitive process in patients with OCD and healthy groups.
In the current cross-sectional analytic study, 43 patients with OCD and 43 healthy individuals matched with gender, age, educational and marital status were selected by convenience sampling method and assessed by Wisconsin Cart Sorting Test (WCST), Paced Auditory Serial Addition Test (PASAT) and Yale-Brown Obsessive Compulsive Scale (Y-BOCS). The obtained data were analyzed with Chi-square, Independent t test, Mann-Whitney U test and Pearson correlation in SPSS version16.
There was no difference between the patients with OCD and the healthy group in demographic characteristics (P>0.05). There was a significant differences between two group on the all subscale of WCST test and PASAT3, PASAT2 tests (P<0.01). These findings indicate that the OCD patient's performance in cognitive process was significantly worse than the healthy controls.
The findings indicate that individuals with OCD suffer from a deficiency in various aspects of cognitive processes. Therefore, paying attention to these deficiencies can make an important contribution to the treatment of these patients.
在最近的研究中，认知过程缺陷已被作为广泛的强迫症（OCD）病因假说之一进行调查。本研究旨在比较强迫症患者与健康组的认知过程。
在当前的横断面分析研究中，采用便利抽样法选取43例强迫症患者和43名在性别、年龄、教育程度及婚姻状况相匹配的健康个体，并通过威斯康星卡片分类测验（WCST）、听觉连续加法测验（PASAT）和耶鲁-布朗强迫症量表（Y-BOCS）进行评估。所获数据在SPSS 16版中采用卡方检验、独立样本t检验、曼-惠特尼U检验和皮尔逊相关性分析。
强迫症患者与健康组在人口统计学特征方面无差异（P>0.05）。两组在WCST测验所有子量表以及PASAT3、PASAT2测验上存在显著差异（P<0.01）。这些结果表明，强迫症患者在认知过程中的表现明显差于健康对照组。
研究结果表明，强迫症患者在认知过程的各个方面存在缺陷。因此，关注这些缺陷可为这些患者的治疗做出重要贡献。
