Hutchins K D, Martino A M, Strick P L
Research Service, V. A. Medical Center, Syracuse, NY 13210.
Exp Brain Res. 1988;71(3):667-72. doi: 10.1007/BF00248761.
We injected wheat germ agglutinin conjugated to horseradish peroxidase into different segments of the spinal cord in order to examine the topographic organization of corticospinal projections from the medial wall of the hemisphere. We observed that substantial projections to the spinal cord originate not only from the supplementary motor area (SMA) in area 6, but also from 2 regions within the cingulate sulcus. The distribution of labeled neurons following tracer injections into different spinal cord segments indicates that corticospinal projections from the SMA and from the 2 cingulate regions are somatotopically organized. These findings together with other recent anatomical observations suggest that the corticospinal projections from the medial wall of the hemisphere provide the basal ganglia and limbic system with a somatotopically organized access to spinal cord mechanisms.
为了研究半球内侧壁皮质脊髓投射的拓扑组织，我们将与辣根过氧化物酶结合的小麦胚芽凝集素注入脊髓的不同节段。我们观察到，向脊髓的大量投射不仅起源于6区的辅助运动区（SMA），还起源于扣带沟内的2个区域。将示踪剂注入不同脊髓节段后标记神经元的分布表明，来自SMA和2个扣带区域的皮质脊髓投射是按躯体定位组织的。这些发现与最近的其他解剖学观察结果共同表明，半球内侧壁的皮质脊髓投射为基底神经节和边缘系统提供了一种按躯体定位组织的进入脊髓机制的途径。
