Macpherson J M, Marangoz C, Miles T S, Wiesendanger M
Exp Brain Res. 1982;45(3):410-6. doi: 10.1007/BF01208601.
The supplementary motor area of three Macaca fascicularis was mapped using intracortical microstimulation (ICMS). Both forelimb and hindlimb movements were evoked using currents of 30 microA or less. However, thresholds for evoking movements were higher than those in the primary motor cortex. Proximal motor effects predominated, but distal joint movements were also elicited. Forelimb points were clustered in mesial cortex of area 6, anterior to the precentral hindlimb and tail region. Distal joint effects were located deep in the cortex, intermingled with proximal effects. Hindlimb response which were less spatially localized, were found both ventral to the forelimb area, in the dorsal bank of the cingulate sulcus, and in mesial cortex, well anterior to area 4. No movements of facial muscles were elicited. Injections of HRP were made into the spinal cord at the cervical level in two animals and the lumbar level in the third one. An area of labelled cells was seen in mesial area 6 which corresponded closely to the region from which ICMS effects were elicited. No movements were evoked from the anterior portions of the fundal region of the cingulate sulcus which were also labelled.
利用皮质内微刺激（ICMS）对三只食蟹猴的辅助运动区进行了定位。使用30微安或更小的电流可诱发出前肢和后肢运动。然而，诱发运动的阈值高于初级运动皮层中的阈值。近端运动效应占主导，但也能引出远端关节运动。前肢点集中在6区的内侧皮质，位于中央前回后肢和尾部区域的前方。远端关节效应位于皮质深部，与近端效应混合在一起。后肢反应的空间定位较差，在前肢区域腹侧、扣带沟背侧以及4区前方的内侧皮质中均有发现。未引出面部肌肉运动。对两只动物在颈部水平、第三只动物在腰部水平的脊髓注射辣根过氧化物酶（HRP）。在6区内侧可见一个标记细胞区域，该区域与通过ICMS引出效应的区域紧密对应。扣带沟底部区域的前部虽也有标记，但未引出运动。
