Becker Gerhild, Merk Constanze S, Meffert Cornelia, Momm Felix
Palliative Care Research Group, Department of Palliative Medicine, University Medical Center Freiburg, Robert-Koch-Str. 3, 79106, Freiburg, Germany.
Qual Life Res. 2014 Sep;23(7):2025-30. doi: 10.1007/s11136-014-0661-4. Epub 2014 Mar 1.
Quality of life (QoL) is one of the most important outcomes in cancer care. Although a number of instruments to measure health-related QoL (HRQoL) exist, there are few suitable instruments to measure individual QoL. The best established instrument is the Schedule for the Evaluation of Individual Quality of Life (SEIQoL). The disadvantage of this questionnaire is its use of semi-structured interviews, which are very time-consuming. The purpose of our study was to transform the SEIQoL into an economical instrument that can be used in clinical trials with large samples.
We developed the SEIQoL-Questionnaire (SEIQoL-Q) on the basis of the SEIQoL-Direct Weighting (SEIQoL-DW) by transforming the interview guide into a written questionnaire. Patients (N = 1,108) in all three phases of radiation treatment (first consultation, ongoing irradiation, and aftercare) were asked to complete the SEIQoL-Q and the European Organization for Research and Treatment of Cancer QLQ-C30.
While the average HRQoL measured by the QLQ-C30 was 55.6, the average SEIQoL-Q index was 59.6. The most important life domain was "physical health," followed by "emotional well-being" and "family." Patients attributed the highest level of satisfaction to "home/housing," followed by "family" and "partnership." Male patients were shown to have a significantly better QoL than females. The SEIQoL-Q index correlates moderately with the QLQ-C30 functioning scale "global quality of life" [r = .42 (p < .001)].
According to our findings, the SEIQoL-Q appears to be a feasible and economical instrument for use in quantitative research among cancer patients in different stages of their disease.
生活质量（QoL）是癌症护理中最重要的结果之一。尽管存在许多用于测量健康相关生活质量（HRQoL）的工具，但适合测量个体生活质量的工具却很少。最成熟的工具是个体生活质量评估量表（SEIQoL）。该问卷的缺点是使用半结构化访谈，这非常耗时。我们研究的目的是将SEIQoL转化为一种经济的工具，可用于大样本的临床试验。
我们在SEIQoL直接加权法（SEIQoL-DW）的基础上开发了SEIQoL问卷（SEIQoL-Q），将访谈指南转化为书面问卷。要求处于放射治疗三个阶段（首次咨询、正在进行的照射和后续护理）的患者（N = 1108）完成SEIQoL-Q和欧洲癌症研究与治疗组织QLQ-C30问卷。
虽然QLQ-C30测量的平均HRQoL为55.6，但平均SEIQoL-Q指数为59.6。最重要的生活领域是“身体健康”，其次是“情绪健康”和“家庭”。患者对“家庭/住房”的满意度最高，其次是“家庭”和“伴侣关系”。结果显示男性患者的生活质量明显优于女性。SEIQoL-Q指数与QLQ-C30功能量表“总体生活质量”呈中度相关[r = 0.42（p < 0.001）]。
根据我们的研究结果，SEIQoL-Q似乎是一种可行且经济的工具，可用于对处于疾病不同阶段的癌症患者进行定量研究。
