Baek S Y, Yamano M, Shiotani Y, Tohyama M
Department of Neuroanatomy, Osaka University Medical School, Japan.
Peptides. 1988 May-Jun;9(3):661-8. doi: 10.1016/0196-9781(88)90179-9.
We studied the distribution of vasoactive intestinal polypeptide-like immunoreactive (VIPLI) fibers in the central amygdaloid (AC) nucleus of the rat, using indirect immunofluorescence and the origins of such fibers using a combination of retrograde tracing with immunocytochemistry. VIPLI fibers formed a dense fiber plexus in the lateral subdivision of the AC nucleus, but other subdivisions showed little immunoreactivity. Destruction of the supramammillary (SuM) region and the adjacent lateral hypothalamus, both of which contained a group of VIPLI neurons, resulted in the marked reduction of VIPLI fibers in the ipsilateral AC nucleus, indicating that many of the fibers in the AC nucleus originate from these two areas. This assumption was supported by the finding that injection of fast blue dye into the AC nucleus labeled the VIPLI neurons in the SuM region and lateral hypothalamus.
我们运用间接免疫荧光法研究了大鼠中央杏仁核（AC）核团中血管活性肠肽样免疫反应性（VIPLI）纤维的分布，并结合逆行追踪与免疫细胞化学方法研究了此类纤维的起源。VIPLI纤维在AC核团的外侧亚区形成了密集的纤维丛，但其他亚区的免疫反应性较弱。损毁同时包含一群VIPLI神经元的乳头体上区（SuM）和相邻的外侧下丘脑，导致同侧AC核团中VIPLI纤维显著减少，这表明AC核团中的许多纤维起源于这两个区域。向AC核团注射快蓝染料标记了SuM区和外侧下丘脑中的VIPLI神经元，这一发现支持了上述假设。
