Inoue H, Shiosaka S, Sasaki Y, Hayashi N, Satoh N, Kamata T, Tohyama M, Shiotani Y
J Neural Transm. 1984;59(3):195-205. doi: 10.1007/BF01250008.
The three-dimensional distribution of vasoactive intestinal polypeptide (VIP)-like immunoreactive (VIPLI) structures in rat stomach and their origins were investigated using the indirect immunofluorescence method in whole mounted tissue. The present study demonstrates a very dense VIPLI fiber meshwork in the circular muscle layer, longitudinal muscle layer and myenteric plexus. In the muscle layers VIPLI immunoreactive fibers run parallel to the muscle. VIPLI fibers are distributed evenly throughout the entire stomach. We have also shown by experimental manipulations that the fibers in the stomach originate from VIPLI neurons in the myenteric plexus.
采用间接免疫荧光法对大鼠胃组织进行整体装片，研究血管活性肠肽（VIP）样免疫反应性（VIPLI）结构的三维分布及其起源。本研究显示，在环肌层、纵肌层和肌间神经丛中有非常密集的VIPLI纤维网络。在肌层中，VIPLI免疫反应性纤维与肌肉平行排列。VIPLI纤维均匀分布于整个胃。我们还通过实验操作表明，胃中的纤维起源于肌间神经丛中的VIPLI神经元。
