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通过对相似性判断进行定标来对健康进行量化。

Quantification of health by scaling similarity judgments.

机构信息

Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.

University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.

出版信息

PLoS One. 2014 Feb 21;9(2):e89091. doi: 10.1371/journal.pone.0089091. eCollection 2014.

Abstract

OBJECTIVE

A new methodology is introduced to scale health states on an interval scale based on similarity responses. It could be well suited for valuation of health states on specific regions of the health continuum that are problematic when applying conventional valuation techniques. These regions are the top-end, bottom-end, and states around 'dead'.

METHODS

Three samples of approximately 500 respondents were recruited via an online survey. Each sample received a different judgmental task in which similarity data were elicited for the top seven health states in the dementia quality of life instrument (DQI). These states were '111111' (no problems on any domain) and six others with some problems (level 2) on one domain. The tasks presented two (dyads), three (triads), or four (quads) DQI health states. Similarity data were transformed into interval-level scales with metric and non-metric multidimensional scaling algorithms. The three response tasks were assessed for their feasibility and comprehension.

RESULTS

In total 532, 469, and 509 respondents participated in the dyads, triads, and quads tasks respectively. After the scaling procedure, in all three response tasks, the best health state '111111' was positioned at one end of the health-state continuum and state '111211' was positioned at the other. The correlation between the metric scales ranged from 0.73 to 0.95, while the non-metric scales ranged from 0.76 to 1.00, indicating strong to near perfect associations. There were no apparent differences in the reported difficulty of the response tasks, but the triads had the highest number of drop-outs.

DISCUSSION

Multidimensional scaling proved to be a feasible method to scale health-state similarity data. The dyads and especially the quads response tasks warrant further investigation, as these tasks provided the best indications of respondent comprehension.

摘要

目的

引入一种新的方法,基于相似性反应,将健康状态在区间尺度上进行标度。当应用传统的估值技术时,对于健康连续体的特定区域(包括健康状态的高端、低端和接近“死亡”的状态),这种方法可能非常适合。

方法

通过在线调查招募了三个约 500 名受访者的样本。每个样本都收到了不同的判断任务,其中为痴呆症生活质量量表(DQI)的前七个健康状态(“111111”(无任何领域问题)和其他六个在一个领域存在一些问题(第 2 级))进行了相似性数据的提取。任务中呈现了两个(对偶)、三个(三元组)或四个(四联)DQI 健康状态。相似性数据通过度量和非度量多维标度算法转换为区间水平标度。评估了这三个响应任务的可行性和理解性。

结果

总共分别有 532、469 和 509 名受访者参加了对偶、三元组和四联任务。在标度过程之后,在所有三个响应任务中,最佳健康状态“111111”位于健康状态连续体的一端,而状态“111211”位于另一端。度量标度之间的相关性在 0.73 到 0.95 之间,而非度量标度在 0.76 到 1.00 之间,表明存在强到近乎完美的关联。响应任务的报告难度没有明显差异,但三元组的退出人数最多。

讨论

多维标度被证明是一种可行的方法,可以对健康状态相似性数据进行标度。对偶和特别是四联响应任务值得进一步研究,因为这些任务提供了对受访者理解的最佳指示。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/470f/3931677/973ca8db2574/pone.0089091.g001.jpg

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