Baraka Mohamed, Steurbaut Stephane, Coomans Danny, Dupont Alain G
* Department of Clinical Pharmacology and Pharmacotherapy, UZ Brussel and Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel , Brussels , Belgium.
Eur J Contracept Reprod Health Care. 2014 Apr;19(2):108-20. doi: 10.3109/13625187.2013.879568. Epub 2014 Mar 4.
To investigate determinants of medication use among multi-ethnic pregnant women.
A total of 641 pregnant women participated in this cross-sectional study in a Brussels university hospital. A questionnaire was used to obtain data on socio-demographic characteristics and medication use. Chi-squared tests and binary logistic regression analyses were performed using SPSS 19.
Medication use during pregnancy (37%) was positively associated with age older than 35 years, Western origin, being born in Belgium, high education and employment status. Highly educated Western women had a greater exposure to drugs with an unknown safety profile than Arab/Turkish and 'Other (non-Western) origins' women. In the latter two groups, low education and nulliparity were the most important determinants of lower drug use. Nulliparous Arab/Turkish women used significantly less medications (17%) during pregnancy than parous women with the same ethnic background (34%; p = 0.024).
Medication use during pregnancy is considerable but differs according to ethnicity. Age, parity, educational level, occupational status and duration of stay in Belgium are important determinants that should be taken into account for risk assessment and preventive measures targeting pregnant women.
调查多民族孕妇用药的决定因素。
共有641名孕妇参与了布鲁塞尔一家大学医院的这项横断面研究。采用问卷调查获取社会人口学特征和用药情况的数据。使用SPSS 19进行卡方检验和二元逻辑回归分析。
孕期用药（37%）与35岁以上年龄、西方血统、出生在比利时、高学历和就业状况呈正相关。与阿拉伯/土耳其裔和“其他（非西方）血统”的女性相比，高学历的西方女性接触安全性未知药物的情况更多。在后面这两组中，低学历和未生育是用药较少的最重要决定因素。未生育的阿拉伯/土耳其裔女性孕期用药（17%）显著少于同种族背景的经产妇（34%；p = 0.024）。
孕期用药情况较为普遍，但因种族而异。年龄、生育状况、教育水平、职业状况和在比利时的居住时长是重要的决定因素，在针对孕妇的风险评估和预防措施中应予以考虑。
