Irino K, Grimont F, Casin I, Grimont P A
Unité 199 Institut National de la Santé et de la Recherche Médicale, Institut Pasteur, Paris, France.
J Clin Microbiol. 1988 Aug;26(8):1535-8. doi: 10.1128/jcm.26.8.1535-1538.1988.
The rRNA gene restriction patterns of 92 isolates of Haemophilus influenzae biogroup aegyptius, associated with conjunctivitis or Brazilian purpuric fever in the State of São Paulo, Brazil, were studied with 16 + 23S rRNA from Escherichia coli as a probe. All strains were classified into 15 patterns. Isolates from Brazilian purpuric fever cases were seen only in patterns 3 (most frequently) and 4 (rarely), whereas isolates from conjunctivitis were found in all 15 patterns. The study demonstrated that rRNA from E. coli can serve as a probe for molecular epidemiology.
用来自大肠杆菌的16 + 23S rRNA作为探针，研究了92株埃及生物群流感嗜血杆菌的rRNA基因限制性图谱，这些菌株与巴西圣保罗州的结膜炎或巴西紫癜热有关。所有菌株被分为15种图谱。巴西紫癜热病例的分离株仅出现在图谱3（最常见）和图谱4（罕见）中，而结膜炎的分离株出现在所有15种图谱中。该研究表明，大肠杆菌的rRNA可作为分子流行病学的探针。
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