Mehmet Burgazlı K, Altay Metin M, Akdere Hakan, Bilgin Mehmet, Kavukcu Ethem, Kill Horst, Päfgen Werner, Kubilay Ertan A
Department of Internal Medicine, Cardiology, Angiology, University Clinic of Giessen, Giessen, Germany.
Department of Urology, Medical Center Wuppertal, Wuppertal, Germany.
J Turk Ger Gynecol Assoc. 2012 Jun 1;13(2):139-41. doi: 10.5152/jtgga.2012.16. eCollection 2012.
Pregnancy, due to its adaptive physiological changes, is a risk factor for deep vein thrombosis. Incidence of thromboembolic complications during pregnancy ranges from 0.76 to 1.72 per 1000 births. We present in this case report a pregnant woman with iliofemoral-popliteal deep vein thrombosis diagnosed at the 35(th) week of her pregnancy, who was treated with vena cava blockage and thrombectomy followed by cesarean section. Unfortunately, a rethrombosis developed in the patient after three days. We determined that the a-v fistula was blocked and not working. We found additionally that the deep vein thrombosis was closing the iliac vein completely on the left side and the blockage descending down through the inferior vena cava inlet with MRI. The patient underwent insertion of a retrievable vena cava filter, two stent implantation to the venous narrowings and surgical iliofemoral venous thrombectomy with concomitant re-creation of a temporary femoral arterio-venous fistula. Anticoagulation therapy with enoxaparine was started after the operation. The patient was discharged with warfarin under control of the INR value, and also with additional compression therapy (compression stockings) from the clinic. Without jeopardizing the mother and the baby, planning a combined surgical procedure, with a multidisciplinary approach is the best way to eliminate the risks of serious complications such as pulmonary embolism and mortality.
由于其适应性生理变化,妊娠是深静脉血栓形成的一个危险因素。妊娠期间血栓栓塞并发症的发生率为每1000例分娩中有0.76至1.72例。在本病例报告中,我们介绍了一名在妊娠第35周被诊断为髂股-腘深静脉血栓形成的孕妇,她接受了腔静脉阻断和血栓切除术,随后进行了剖宫产。不幸的是,患者在三天后再次发生血栓形成。我们确定动静脉瘘被阻塞且不起作用。此外,通过磁共振成像我们发现深静脉血栓完全阻塞了左侧髂静脉,并且阻塞通过下腔静脉入口向下延伸。患者接受了可回收下腔静脉滤器置入、对静脉狭窄部位进行两次支架植入以及手术髂股静脉血栓切除术,并同时重新建立了临时股动静脉瘘。术后开始使用依诺肝素进行抗凝治疗。患者在国际标准化比值(INR)值的监测下出院时服用华法林,并且还从诊所接受了额外的加压治疗(加压袜)。在不危及母婴的情况下,采用多学科方法规划联合手术程序是消除肺栓塞和死亡等严重并发症风险的最佳方法。