Kanchiswamy Chidananda Nagamangala, Malnoy Mickael, Occhipinti Andrea, Maffei Massimo E
Research and Innovation Centre Genomics and Biology of Fruit Crop Department, Fondazione Edmund Mach (FEM), Istituto Agrario San Michele (IASMA), Via Mach 1, 38010 San Michele all'Adige (TN), Italy.
Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Via Quarello 15/A, 10135 Turin, Italy.
Int J Mol Sci. 2014 Mar 4;15(3):3842-59. doi: 10.3390/ijms15033842.
The calcium ion (Ca2+) is a versatile intracellular messenger. It provides dynamic regulation of a vast array of gene transcriptions, protein kinases, transcription factors and other complex downstream signaling cascades. For the past six decades, intracellular Ca2+ concentration has been significantly studied and still many studies are under way. Our understanding of Ca2+ signaling and the corresponding physiological phenomenon is growing exponentially. Here we focus on the improvements made in the development of probes used for Ca2+ imaging and expanding the application of Ca2+ imaging in plant science research.
钙离子（Ca2+）是一种多功能的细胞内信使。它对大量基因转录、蛋白激酶、转录因子及其他复杂的下游信号级联反应进行动态调控。在过去的六十年里，细胞内Ca2+浓度得到了广泛研究，目前仍有许多研究正在进行。我们对Ca2+信号传导及相应生理现象的理解正在呈指数级增长。在此，我们重点关注用于Ca2+成像的探针开发所取得的进展，以及扩大Ca2+成像在植物科学研究中的应用。
