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用于治疗累及主动脉弓的复杂B型主动脉夹层的冰冻象鼻技术:多中心早期经验

The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience.

作者信息

Weiss Gabriel, Tsagakis Konstantinos, Jakob Heinz, Di Bartolomeo Roberto, Pacini Davide, Barberio Giuseppe, Mascaro Jorge, Mestres Carlos-A, Sioris Thanos, Grabenwoger Martin

机构信息

Department of Cardiovascular Surgery, Hospital Hietzing, Vienna, Austria

Department of Cardiac Surgery, University Hospital Essen, Essen, Germany.

出版信息

Eur J Cardiothorac Surg. 2015 Jan;47(1):106-14; discussion 114. doi: 10.1093/ejcts/ezu067. Epub 2014 Mar 5.

Abstract

OBJECTIVES

Providing effective treatment for complicated type B aortic dissection (AD) with concomitant pathologies of the aortic arch or ascending aorta is challenging, especially if the aortic anatomy is contraindicated for thoracic endovascular aortic repair (TEVAR). We present the early results of a multicentre study using the frozen elephant trunk (FET) technique for type B AD.

METHODS

From January 2005 to March 2013, data from 465 patients who had undergone treatment with the FET technique were collected in the database of the International E-vita Open Registry. From this cohort, 57 patients who had a primary indication for surgery for type B AD were included in the present study. Their mean age was 58±12 years, and 72% had a chronic dissection. All operations were performed in circulatory arrest and bilateral antegrade cerebral perfusion. Computed aortic imaging was performed for false lumen (FL) evaluation during the follow-up.

RESULTS

The in-hospital mortality rate was 14% (8/57). Stroke and spinal cord injury occurred in 6 (10%) and 2 patients (4%), respectively. The rate of immediate FL thrombosis at the level of the stent graft was 75% (40/53) and increased to 97% (41/42) during the follow-up period (23±19 months). Distally, at the level of the abdominal aorta, the FL remained patent in 50% (21/42) of patients. The 1- and 3-year survival was 81 and 75%, respectively.

CONCLUSION

The FET technique is a feasible therapeutic option for complicated type B AD with involvement of the aortic arch if TEVAR is contraindicated. In contrast to conventional aortic surgery via a lateral thoracotomy, the FET procedure can provide simultaneous treatment of the ascending aorta and aortic arch.

摘要

目的

为合并主动脉弓或升主动脉病变的复杂性B型主动脉夹层(AD)提供有效治疗具有挑战性,特别是当主动脉解剖结构不适合胸主动脉腔内修复术(TEVAR)时。我们展示了一项使用冰冻象鼻(FET)技术治疗B型AD的多中心研究的早期结果。

方法

2005年1月至2013年3月,在国际E-vita开放注册数据库中收集了465例行FET技术治疗患者的数据。从该队列中,本研究纳入了57例有B型AD手术主要指征的患者。他们的平均年龄为58±12岁,72%为慢性夹层。所有手术均在循环停止和双侧顺行脑灌注下进行。随访期间进行主动脉计算机成像以评估假腔(FL)。

结果

住院死亡率为14%(8/57)。分别有6例(10%)和2例(4%)发生中风和脊髓损伤。支架移植物水平的即刻FL血栓形成率为75%(40/53),随访期间(23±19个月)升至97%(41/42)。在远端腹主动脉水平,50%(21/42)的患者FL仍保持通畅。1年和3年生存率分别为81%和75%。

结论

如果TEVAR禁忌,FET技术是治疗累及主动脉弓的复杂性B型AD的可行治疗选择。与通过侧胸壁切开术的传统主动脉手术相比,FET手术可同时治疗升主动脉和主动脉弓。

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