慢性心力衰竭患者对热应激的心血管反应
Cardiovascular responses to heat stress in chronic heart failure.
作者信息
Cui Jian, Sinoway Lawrence I
机构信息
Penn State Hershey Heart and Vascular Institute, H047, Milton S. Hershey Medical Center, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA,
出版信息
Curr Heart Fail Rep. 2014 Jun;11(2):139-45. doi: 10.1007/s11897-014-0191-y.
Abstract
Clinical reports have suggested that patients with heart diseases may be particularly vulnerable to heat injury. This review examines the effects of heat stress on cardiovascular and autonomic functions in patients with chronic heart failure (CHF). Laboratory investigations have shown that cutaneous vasodilator responses to heating are impaired in patients, whereas activation of skin sympathetic nerve activation is not attenuated in CHF as compared to controls. Attenuated cutaneous vasodilation may increase the risk of a heat related illness when CHF subjects are exposed to hyperthermic conditions.
摘要
临床报告表明，心脏病患者可能特别容易受到热损伤。本综述探讨了热应激对慢性心力衰竭（CHF）患者心血管和自主神经功能的影响。实验室研究表明，患者对加热的皮肤血管舒张反应受损，而与对照组相比，CHF患者皮肤交感神经激活并未减弱。当CHF患者暴露于高温环境时，皮肤血管舒张减弱可能会增加与热相关疾病的风险。
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