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网状黄斑疾病是脉络膜毛细血管灌注问题吗?

Is reticular macular disease a choriocapillaris perfusion problem?

作者信息

A Martillo Miguel, Marsiglia Marcela, D Lee Michele, Pumariega Nicole, Bearelly Srilaxmi, Smith R Theodore

机构信息

Department of Ophthalmology, New York University, New York, USA.

Department of Ophthalmology, New York University, New York, USA ; Department of Ophthalmology, Harkness Eye Institute, Columbia University, New York, USA ; LuEsther T. Mertz Retinal Research Center and Manhattan Eye, Ear and Throat Hospital, New York USA.

出版信息

Med Hypothesis Discov Innov Ophthalmol. 2012 Summer;1(2):37-41.

PMID:24600618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3939745/
Abstract

The etiology of reticular macular disease (RMD), a sub-phenotype of age-related macular degeneration (AMD), is controversial and has not been clarified. RMD is suspected to be a multifactorial, complex disease with genetic, environmental, and systemic factors playing an important role in its origin. Findings from combinations of different imaging modalities suggest that the pattern that characterizes this condition is associated with an alteration of the choriocapillaris blood flow. If the choroid is indeed affected in RMD, the possible linkage with inflammatory or other systemic diseases could be better supported.

摘要

网状黄斑疾病(RMD)是年龄相关性黄斑变性(AMD)的一种亚型,其病因存在争议且尚未明确。RMD被怀疑是一种多因素的复杂疾病,遗传、环境和全身因素在其发病过程中起重要作用。不同成像方式组合的研究结果表明,这种疾病的特征性模式与脉络膜毛细血管血流改变有关。如果脉络膜在RMD中确实受到影响,那么与炎症或其他全身性疾病的可能联系将得到更好的支持。

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