Djedovic Samed, Mujanovic Emir, Djedovic Muhamed, Rajkovic Stojan, Jahic Mirza, Tosic Zoran
BH Heart Center Tuzla, Tuzla, Bosnia and Hercegovina.
Department for Vascular Surgery, Clinical Center of University of Sarajevo, Sarajevo, Bosnia and Hercegovina.
Med Arch. 2013;67(5):351-3. doi: 10.5455/medarh.2013.67.351-353.
The number of patients undergoing coronary artery bypass grafting (coronary artery bypass grafting-CABG) older than 70 years is increasing. Cardiac surgeons are investigate applicability of alternative and less invasive methods such as surgery without the use of cardiopulmonary bypass (CPB). The aim of this study was to compare the peri- and postoperative results of CABG in elderly patients operated with and without CPB.
The study included subjects older than 70 years, who underwent coronary bypass surgery at the BH Heart Center Tuzla in the period from August 2008 to August 2010, divided into two groups. Group A consisted of 50 patients operated without CPB, group B 50 patients operated with CPB, adjusted by sex, left ventricular ejection fraction values, EuroSCORE, and the number of bypass grafts was made.
In the group treated without the use CPB there were significantly lower values of the time-duration of mechanical ventilation, length of stay in the Intensive Care Unit (ICU), the amount of postoperative bleeding and blood recovered, the length of hospital stay, levels of serum creatinine, C-reactive protein and creatine kinase MB fraction.
CABG without the use of CPB has a number of advantages over the method with CPB in elderly patients, which is evident from the lower values of renal and inflammatory parameters and markers of myocardial lesion, less time spent on a ventilator, shorter length of stay in the ICU and total hospitalization time, less postoperative bleeding and blood transfusion.
接受冠状动脉搭桥术(冠状动脉搭桥术 - CABG)的70岁以上患者数量正在增加。心脏外科医生正在研究诸如不使用体外循环(CPB)的手术等替代且侵入性较小的方法的适用性。本研究的目的是比较在有或无CPB情况下接受手术的老年患者冠状动脉搭桥术的围手术期和术后结果。
该研究纳入了2008年8月至2010年8月期间在图兹拉BH心脏中心接受冠状动脉搭桥手术的70岁以上患者,分为两组。A组由50例未使用CPB进行手术的患者组成,B组由50例使用CPB进行手术的患者组成,根据性别、左心室射血分数值、欧洲心脏手术风险评估系统(EuroSCORE)以及搭桥血管数量进行了调整。
在未使用CPB治疗的组中,机械通气持续时间、重症监护病房(ICU)住院时间、术后出血量和回收血量、住院时间、血清肌酐水平、C反应蛋白和肌酸激酶MB同工酶水平显著较低。
在老年患者中,不使用CPB的冠状动脉搭桥术比使用CPB的方法具有许多优势,这从肾脏和炎症参数以及心肌损伤标志物的较低值、在呼吸机上花费的时间较少、在ICU的住院时间和总住院时间较短、术后出血和输血较少可以明显看出。