Khar'kovskaia N A, Shipova L Ia, Faktor V M, Khrustalev S A
Eksp Onkol. 1988;10(4):37-9.
The spontaneous hepatomas of male mice (CBA X C57B1/6)F1 were studied using complex cytologic, histologic, immunochemical, and cytochemical methods. The AFP was detected in trace amount in the serum of tumour-bearing mice and in single cells of hepatomas. As a rule the hepatocarcinoma cells have the polymodal DNA distribution (2C-8C) with major peak of 4 C (in 18 out of 26 cases). More rarely the tumours with predominant diploid and octoploid cells were observed.
采用复杂的细胞学、组织学、免疫化学和细胞化学方法，对雄性（CBA×C57B1/6）F1小鼠的自发性肝癌进行了研究。在荷瘤小鼠血清和肝癌单细胞中检测到微量甲胎蛋白。通常，肝癌细胞具有多峰DNA分布（2C - 8C），主峰为4C（26例中有18例）。较少观察到以二倍体细胞和八倍体细胞为主的肿瘤。
