Kim S J, Jung J K, Kang B C, Namkoong S E, Lee J W
Department of Obstetrics and Gynecology, Catholic University Medical College, Seoul, Korea.
Int J Gynaecol Obstet. 1988 Oct;27(2):193-8. doi: 10.1016/0020-7292(88)90007-0.
In vivo responses of trophoblasts to luteinizing hormone releasing hormone (LHRH) stimulation in 48 gestational trophoblastic disease patients were observed. Serum beta human chorionic gonadotropin (beta-hCG) levels after LHRH injection were significantly increased in patients with hCG values between 5 and 20 mIU/ml (minimal resistance group) but not in patients whose hCG levels were less than 5 mIU/ml (possible remission group). The sensitivity, specificity and the predictive values of LHRH stimulation test were 75.0, 91.3 and 95.5% in the possible remission group and 87.5, 20.0 and 77.8% in the minimal resistance group.
观察了48例妊娠滋养细胞疾病患者的滋养细胞对促黄体生成激素释放激素（LHRH）刺激的体内反应。LHRH注射后，hCG值在5至20 mIU/ml之间的患者（最小抵抗组）血清β-人绒毛膜促性腺激素（β-hCG）水平显著升高，但hCG水平低于5 mIU/ml的患者（可能缓解组）则未升高。LHRH刺激试验在可能缓解组的敏感性、特异性和预测值分别为75.0%、91.3%和95.5%，在最小抵抗组分别为87.5%、20.0%和77.8%。
