Berg-Hansen P, Moen S M, Harbo H F, Celius E G
Department of Neurology, Oslo University Hospital, Ullevål and Institute of Clinical Medicine, University of Oslo, Norway
Department of Neurology, Oslo University Hospital, Ullevål and Institute of Clinical Medicine, University of Oslo, Norway.
Mult Scler. 2014 Nov;20(13):1780-2. doi: 10.1177/1352458514525871. Epub 2014 Mar 6.
The prevalence of multiple sclerosis (MS) is increasing, and the presence of a latitude gradient for MS risk is still discussed. We present the first nationwide prevalence estimates for Norway, spanning the latitudes from 58-71 degrees North, in order to identify a possible latitude gradient. Information from the Oslo MS Registry and the Norwegian MS Registry and Biobank was combined with data from the Norwegian Patient Registry, the Norwegian Prescription Database and Statistics Norway. We estimated a crude prevalence of 203/100,000 on 1 January 2012. The prevalence in the Northern and Southern regions were not significantly different. MS prevalence in Norway is among the highest reported worldwide. We found no evidence of a latitude gradient.
多发性硬化症（MS）的患病率正在上升，MS风险的纬度梯度的存在仍在讨论中。我们给出了挪威首个全国性患病率估计值，范围涵盖北纬58至71度，以确定是否存在可能的纬度梯度。来自奥斯陆MS登记处、挪威MS登记处和生物样本库的信息与来自挪威患者登记处、挪威处方数据库和挪威统计局的数据相结合。我们估计2012年1月1日的粗患病率为203/10万。北部和南部地区的患病率没有显著差异。挪威的MS患病率在全球报告的患病率中处于最高水平。我们没有发现纬度梯度的证据。
