Lasisi Taye Jemilat, Adisa Akinyele Olumuyiwa, Olusanya Adeola Adenike
BDS, FMCDS, Department of Oral Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria, Tel: +2348053513471; e-mail:
Oral Health Dent Manag. 2014 Mar;13(1):41-4.
Fibro-osseous lesion is a broad term for a diverse group of jaw disorders characterized by the replacement of normal bone by a benign fibrous connective tissue matrix. The present study reviewed the clinico-pathologic characteristics of all biopsied cases of fibro-osseous lesions at our hospital from 1990 to 2011, which we hope will serve as a reference database regionally.
A retrospective clinicopathological review of all histologically diagnosed cases of jaw fibro-osseous lesions seen at our Hospital between January 1990 and December 2011.
A total of one hundred and twenty one fibro-osseous lesions of jaws were histological diagnosed in the 22-year period. The lesions documented included ossifying fibroma (62%), fibrous dysplasia (37.2%) and florid cemento-osseous dysplasia (0.8%). Fibro-osseous lesions of jaws were more in females (61.2%) than males (38.8%), giving a male to female ratio of 1:1.6.
Fibro-osseous lesions of jaw are a diverse group and since it may not be possible to adequately separate them histologically, the development of a more rigorous clinical algorithm as indicated in this study is essential in reaching a final diagnosis especially in resource-limited settings.
纤维-骨病变是一组多种颌骨疾病的统称,其特征是正常骨被良性纤维结缔组织基质所替代。本研究回顾了我院1990年至2011年间所有经活检的纤维-骨病变病例的临床病理特征,希望能成为该地区的参考数据库。
对我院1990年1月至2011年12月间所有经组织学诊断的颌骨纤维-骨病变病例进行回顾性临床病理分析。
在这22年期间,共组织学诊断出121例颌骨纤维-骨病变。记录的病变包括骨化性纤维瘤(62%)、骨纤维异常增殖症(37.2%)和 florid 骨水泥性骨发育异常(0.8%)。颌骨纤维-骨病变女性(61.2%)多于男性(38.8%),男女比例为1:1.6。
颌骨纤维-骨病变是一组多样的疾病,由于在组织学上可能无法充分区分它们,因此如本研究所示,制定更严格的临床诊断流程对于最终诊断至关重要,尤其是在资源有限的情况下。