Fjällbrant B, Nilsson S
Int J Fertil. 1977;22(4):255-6.
Although autoimmunization to spermatozoa is a cause of male infertility, the cause of antibody formation is unknown in most cases. It has been shown that the titer is usually unchanged for as much as 16 years in the same individual. Trials to reduce the titer with varying methods have not been successful. A new possibility of treatment was indicated by the finding of a higher incidence of prostatitis in men with sperm antibodies than in a control group. Following treatment of prostatitis we observed a reduction of the antibody titer in eight cases. In five cases the cervical mucus penetrating capacity of the spermatozoa improved, and conception occurred.
虽然精子自身免疫是男性不育的一个原因，但在大多数情况下，抗体形成的原因尚不清楚。研究表明，同一个体的抗体滴度通常在长达16年的时间里保持不变。用不同方法降低抗体滴度的试验均未成功。精子抗体阳性男性前列腺炎发病率高于对照组，这一发现提示了一种新的治疗可能性。前列腺炎治疗后，我们观察到8例患者抗体滴度降低。5例患者精子穿透宫颈黏液的能力得到改善并受孕。
