Lu Yu-Fei, Liu Zhi-Cai, Li Zhong-Hong, Ma Wen-Hao, Wang Fu-Rang, Zhang Ya-Bing, Lu Jian-Bang
Department of Oncology, Shandong University, Departments of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan, China E-mail :
Asian Pac J Cancer Prev. 2014;15(3):1419-22. doi: 10.7314/apjcp.2014.15.3.1419.
To summarize the endoscopic screening findings in high-risk population of esophageal and gastric carcinoma and analyze influential factors related to screening.
In seven selected cities and counties with high incidences of esophageal carcinoma, people at age of 40-69 were set as the target population. Those with gastroscopy contradictions were excluded, and all who were voluntary and willing to comply with the medical requirements were subjected to endoscopic screening and histological examination for esophageal, gastric cardia and gastric carcinoma in accordance with national technical manual for early detection and treatment of cancer.
In three years, 36,154 people were screened, and 16,847 (46.60%) cases were found to have precancerous lesions. A total of 875 cases were found to have cancers (2.42%), and among them 739 cases had early stage with an early diagnosis rate is 84.5%. Some 715 patients underwent prompt treatment and the success rate was 81.8%.
In a high-risk population of esophageal and gastric carcinoma, it is feasible to implement early detection and treatment by endoscopic screening. Screening can identify potential invasive carcinoma, early stage carcinoma and precancerous lesions, improving efficacy through early detection and treatment. The exploratory analysis of related influential factors will help broad implementation of early detection and treatment for esophageal and gastric carcinoma.
总结食管癌和胃癌高危人群的内镜筛查结果，并分析与筛查相关的影响因素。
在7个食管癌高发的选定市县，将40 - 69岁人群作为目标人群。排除有胃镜检查禁忌证者，所有自愿且愿意遵守医疗要求的人员按照国家癌症早诊早治技术手册接受食管、贲门和胃癌的内镜筛查及组织学检查。
三年内，共筛查36154人，发现16847例（46.60%）有癌前病变。共发现875例癌症（2.42%），其中739例为早期，早期诊断率为84.5%。约715例患者接受了及时治疗，成功率为81.8%。
在食管癌和胃癌高危人群中，通过内镜筛查实施早诊早治是可行的。筛查可识别潜在浸润癌、早期癌和癌前病变，通过早诊早治提高疗效。对相关影响因素的探索性分析将有助于食管癌和胃癌早诊早治的广泛实施。
