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下唇鳞状细胞癌的外科治疗:109例经验

Surgical management of squamous cell carcinoma of the lower lip: an experience of 109 cases.

作者信息

Rena Wenhao, Lia Yin, Liua Changyang, Qianga Cui, Zhang Linmei, Gaoa Ling, Wangb Zhi, Zhia Keqian

机构信息

Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Xi'an Jiaotong, University College of Medicine, Number 98, West Fifth Road, Xi'an, ShaanXi, People's Republic of China, 710004,

出版信息

Med Oral Patol Oral Cir Bucal. 2014 Jul 1;19(4):e398-402. doi: 10.4317/medoral.19595.

Abstract

OBJECTIVE

We are presenting our experience collected from a series of 109 cases with SCC of the lower lip focusing on clinical features of patients and surgical approach.

STUDY DESIGN

We retrospectively analyzed medical records of patients diagnosed with Squamous Cell Carcinoma (SCC) of the lower lip at the Oral and Maxillofacial surgery at Xi'an Jiaotong University during a period between 1999 and 2008.

RESULTS

A total of 109 patients with lip cancer were included in the study. When no frozen-section test was performed, the neoplasia was removed with a margin of at least 6 mm. Different surgical techniques were used for lip reconstruction after tumor excision. Neck dissection was performed in all patients with clinically palpable lymph nodes. Median follow-up was 38 months. During follow-up, recurrence occurred in 5 patients, 3 patients developed neck metastases, distant metastases developed in 1 patient. Five patients died during observation period.

CONCLUSIONS

The patient-related and defect-related issues must be taken into consideration during reconstruction for surgical defect. For N0 patients, we recommend wait-and-see policy. Early detection, careful follow-up and prompt neck is essential for the successful treatment.

摘要

目的

我们报告了从109例下唇鳞状细胞癌患者中收集的经验,重点关注患者的临床特征和手术方法。

研究设计

我们回顾性分析了1999年至2008年期间在西安交通大学口腔颌面外科诊断为下唇鳞状细胞癌(SCC)的患者的病历。

结果

本研究共纳入109例唇癌患者。在未进行冰冻切片检查时,肿瘤切除时切缘至少为6mm。肿瘤切除后采用不同的手术技术进行唇部重建。所有临床可触及淋巴结的患者均进行了颈部清扫。中位随访时间为38个月。随访期间,5例患者复发,3例患者发生颈部转移,1例患者发生远处转移。5例患者在观察期内死亡。

结论

在手术缺损重建过程中必须考虑与患者相关和与缺损相关的问题。对于N0患者,我们建议采取观察等待策略。早期发现、仔细随访和及时的颈部处理对于成功治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bf/4119317/3c4f11711442/medoral-19-e398-g001.jpg

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