Prigent Amélie, Auraaen Ane, Kamendje-Tchokobou Blaise, Durand-Zaleski Isabelle, Chevreul Karine
AP-HP, URC Eco Ile-de-France, 1, Place du Parvis Notre Dame, Paris F-75004, France.
Centre Hospitalier Départemental Georges Daumézon, 1 route de Chanteau, Fleury-les-Aubrais F-45400, France.
Int J Environ Res Public Health. 2014 Mar 7;11(3):2804-17. doi: 10.3390/ijerph110302804.
There is a lack of comparable health-related quality of life (HRQoL) and utility data across all mental disorders and all inpatient and outpatient settings. Our objective was to investigate the HRQoL and utility scores of people with mental disorders in France, treated in outpatient and inpatient settings, and to identify the HRQoL and utility score losses attributable to mental disorders compared to the non-mentally ill general population. A cross-sectional survey was conducted to assess HRQoL (SF-12) and utility scores of patients with mental disorders and followed in four psychiatric sectors in France. Scores were described by demographic and clinical characteristics and were then adjusted on age and gender and compared with those of the non-mentally ill general population. Median HRQoL and utility scores were significantly lower in patients with mental disorders than in the non-mentally ill general population; median differences amounted to 5.4 for the HRQoL physical score, to 11.8 for the HRQoL mental score and to 0.125 for the utility score. Our findings underscore the negative impact of mental disorders on HRQoL in France and provide a baseline to assess the global impact of current and future organizational changes in the mental health care system.
目前缺乏针对所有精神障碍以及所有住院和门诊环境的、具有可比性的健康相关生活质量（HRQoL）和效用数据。我们的目标是调查在法国门诊和住院环境中接受治疗的精神障碍患者的HRQoL和效用得分，并确定与非精神疾病的普通人群相比，精神障碍导致的HRQoL和效用得分损失。我们进行了一项横断面调查，以评估法国四个精神科部门中精神障碍患者的HRQoL（SF - 12）和效用得分。得分根据人口统计学和临床特征进行描述，然后根据年龄和性别进行调整，并与非精神疾病的普通人群的得分进行比较。精神障碍患者的HRQoL和效用得分中位数显著低于非精神疾病的普通人群；HRQoL身体得分的中位数差异为5.4，HRQoL心理得分的中位数差异为11.8，效用得分的中位数差异为0.125。我们的研究结果强调了精神障碍对法国HRQoL的负面影响，并为评估当前和未来精神卫生保健系统组织变革的总体影响提供了一个基线。
