Prigent Amélie, Kamendje-Tchokobou Blaise, Chevreul Karine
AP-HP, URC Eco Ile-de-France, 1, place du parvis Notre Dame, 75004, Paris, France.
University Paris Diderot, Sorbonne Paris Cité, ECEVE, UMR 1123, 75010, Paris, France.
Qual Life Res. 2017 Nov;26(11):3035-3048. doi: 10.1007/s11136-017-1623-4. Epub 2017 Jun 21.
Health-related quality of life (HRQoL) is a widely used concept in the assessment of health care. Some generic HRQoL instruments, based on specific algorithms, can generate utility scores which reflect the preferences of the general population for the different health states described by the instrument. This study aimed to investigate the relationships between utility scores and potentially associated factors in patients with mental disorders followed in inpatient and/or outpatient care settings using two statistical methods.
Patients were recruited in four psychiatric sectors in France. Patient responses to the SF-36 generic HRQoL instrument were used to calculate SF-6D utility scores. The relationships between utility scores and patient socio-demographic, clinical characteristics, and mental health care utilization, considered as potentially associated factors, were studied using OLS and quantile regressions.
One hundred and seventy six patients were included. Women, severely ill patients and those hospitalized full-time tended to report lower utility scores, whereas psychotic disorders (as opposed to mood disorders) and part-time care were associated with higher scores. The quantile regression highlighted that the size of the associations between the utility scores and some patient characteristics varied along with the utility score distribution, and provided more accurate estimated values than OLS regression.
The quantile regression may constitute a relevant complement for the analysis of factors associated with utility scores. For policy decision-making, the association of full-time hospitalization with lower utility scores while part-time care was associated with higher scores supports the further development of alternatives to full-time hospitalizations.
健康相关生活质量(HRQoL)是医疗保健评估中广泛使用的概念。一些基于特定算法的通用HRQoL工具可以生成效用分数,这些分数反映了普通人群对该工具所描述的不同健康状态的偏好。本研究旨在使用两种统计方法调查住院和/或门诊护理环境中精神障碍患者的效用分数与潜在相关因素之间的关系。
在法国的四个精神科招募患者。患者对SF - 36通用HRQoL工具的回答用于计算SF - 6D效用分数。使用普通最小二乘法(OLS)和分位数回归研究效用分数与患者社会人口统计学、临床特征以及被视为潜在相关因素的精神卫生保健利用之间的关系。
纳入了176名患者。女性、重症患者和全职住院患者往往报告较低的效用分数,而精神障碍(与情绪障碍相反)和兼职护理与较高分数相关。分位数回归强调,效用分数与一些患者特征之间的关联大小随效用分数分布而变化,并且比分位数回归提供更准确的估计值。
分位数回归可能是分析与效用分数相关因素的一种相关补充。对于政策决策,全职住院与较低效用分数相关,而兼职护理与较高分数相关,这支持进一步发展全职住院替代方案。