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机器人辅助腹腔镜手术治疗深部浸润性子宫内膜异位症:国际多中心回顾性研究

Robot-assisted laparoscopy for deep infiltrating endometriosis: international multicentric retrospective study.

作者信息

Collinet Pierre, Leguevaque Pierre, Neme Rosa Maria, Cela Vito, Barton-Smith Peter, Hébert Thomas, Hanssens Sandy, Nishi Hirotaka, Nisolle Michelle

机构信息

Maternity ward, Hôpital Jeanne de Flandre, Centre Hospitalier Régional Universitaire de Lille (CHRU of Lille), 2 Avenue Eugène Avinée, 59037, Lille Cedex, France.

出版信息

Surg Endosc. 2014 Aug;28(8):2474-9. doi: 10.1007/s00464-014-3480-3. Epub 2014 Mar 8.

Abstract

BACKGROUND

This study aimed to assess the interest in robot-assisted laparoscopy for deep infiltrating endometriosis and to investigate the perioperative results.

METHODS

From November 2008 to April 2012, 164 women with stage 4 endometriosis who underwent robot-assisted laparoscopy (da Vinci Intuitive Surgical System) were included by to eight international participating clinical centers. This study evaluated the procedures performed, the duration of the intervention, the complications, the recurrence, and the impact on fertility.

RESULTS

The average operative time was 180 min. The main complications were laparotomy (n = 1, 0.6%), sutured bowel injury (n = 2, 1.2%), transfusion for a 2,300-ml bleed (n = 1), prolonged urinary catheterization (n = 1, 0.6%), ureter-bladder anastomotic leak (n = 1, 0.6%), and ureteral fistula after ureterolysis (n = 2, 1.2%). The reoperation rate was 1.8% (n = 3). The mean follow-up period was 10.2 months. A full recovery was experienced by 86.7% (98/113) of the patients. After surgery, 41.2% (42/102) of the patients had a desire for pregnancy, and 28.2% (11/39) of them became pregnant.

CONCLUSION

This study analyzed the largest series of robot-assisted laparoscopies for deep infiltrating endometriosis published in the literature. No increase in surgical time, blood loss, or intra- or postoperative complications was observed. The interest in robot-assisted laparoscopy for deep infiltrating endometriosis seems to be promising.

摘要

背景

本研究旨在评估机器人辅助腹腔镜手术治疗深部浸润性子宫内膜异位症的应用价值,并探讨围手术期结果。

方法

2008年11月至2012年4月,8个国际参与临床中心纳入了164例接受机器人辅助腹腔镜手术(达芬奇直观手术系统)的4期子宫内膜异位症女性患者。本研究评估了手术操作、干预持续时间、并发症、复发情况以及对生育的影响。

结果

平均手术时间为180分钟。主要并发症包括剖腹手术(n = 1,0.6%)、肠缝合损伤(n = 2,1.2%)、因2300毫升出血输血(n = 1)、导尿时间延长(n = 1,0.6%)、输尿管膀胱吻合口漏(n = 1,0.6%)以及输尿管松解术后输尿管瘘(n = 2,1.2%)。再次手术率为1.8%(n = 3)。平均随访期为10.2个月。86.7%(98/113)的患者完全康复。术后,41.2%(42/102)的患者有妊娠意愿,其中28.2%(11/39)成功妊娠。

结论

本研究分析了文献中发表的关于机器人辅助腹腔镜手术治疗深部浸润性子宫内膜异位症的最大系列病例。未观察到手术时间、失血量或术中及术后并发症增加。机器人辅助腹腔镜手术治疗深部浸润性子宫内膜异位症的应用前景似乎很广阔。

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